Publications by authors named "Yuryanni Rodriguez"

Article Synopsis
  • Type I cells in taste buds make up about half the cell population and have been largely understudied in terms of their function.
  • Research using GCaMP3 mice revealed that Type I cells respond to ATP but not to serotonin or direct taste stimuli, indicating their role in chemosensory activation.
  • The study suggests that Type I cells contribute to taste signaling by responding to ATP released by Type II cells, potentially acting similarly to glial cells in the central nervous system.
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Collapsin Response Mediator Protein 2 (CRMP2) is an intracellular protein involved in axon and dendrite growth and specification. In this study, CRMP2 was identified in a conditioned media derived from degenerated sciatic nerves (CM). On cultured rat hippocampal neurons, acute extracellular application of CM or partially purified recombinant CRMP2 produced an increase in cytoplasmic calcium.

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Severe to profound hearing impairment affects 1 of every 1000 newborn children each year. Inheritance accounts for 60% of these cases, of which 70% are nonsyndromic. The most common cause of autosomal recessive nonsyndromic hearing loss (ARNSHL) is mutation in GJB2, a gene on chromosome 13, which encodes a gap junction protein named Connexin 26.

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