Publications by authors named "Yury Bokov"
Article Synopsis
- Arterial inflammation from atherosclerosis is a leading global cause of death, with HDAC9 identified as a key player in the disease's progression and complications like stroke and heart attacks.*
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- Research using hyperlipidemic mice shows that inhibiting HDAC9 with a small molecule (TMP195) reduces inflammation and stabilizes atherosclerotic plaques by affecting macrophage and endothelial cell behavior.*
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- TMP195 not only mitigates lesions and their vulnerability but also lowers inflammatory markers in monocytes from patients with atherosclerosis, indicating its potential as a therapeutic approach for atheroprotection.*
