Publications by authors named "Yuruchen Zhu"
Solid tumors cause 90% of cancers and remain the primary cause of mortality. However, treating solid tumors presents significant challenges due to the complex tumor microenvironment and drug resistance, leading to inadequate treatment targeting and severe side effects. Surgery, radiotherapy, and chemotherapy Although it is an effective method for the treatment of solid tumors, it can lead to organ dysfunction and affect patient prognosis.
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- MSC-EVs are promising natural nanomedicines, but how they are secreted and delivered is not fully understood.
- The stiffness of the extracellular matrix (ECM) influences the sorting of proteins and lipids into MSC-EVs, affecting their secretion and uptake by immune cells like macrophages.
- This research highlights the relationship between ECM properties and MSC-EV behavior, offering insights for designing better biomedical materials.