Publications by authors named "Yuriy V Doludin"

Article Synopsis
  • This study explores how gut bacteria influence cardiovascular diseases, focusing on harmful metabolites linked to conditions like coronary artery disease (CAD) and heart failure with reduced ejection fraction (HFrEF).
  • It involved 189 participants categorized into three groups: CAD (93), HFrEF (43), and healthy controls (53), using advanced techniques like network analysis and machine learning to analyze gut microbiota and its relationship to these heart conditions.
  • Key findings showed significant differences in gut microbiota composition and diversity, with specific microbial features and metabolites, such as lower TMAO levels in CAD and HFrEF groups, suggesting a complex interaction between gut health and cardiovascular disease.
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Purpose: Preclinical evaluation of and transcript simultaneous detection in urine to diagnose clinical significant prostate cancer (prostate cancer with Gleason score ≥7) in a Russian cohort.

Patients And Methods: We analyzed urine samples of patients with a total serum PSA ≥2 ng/mL: 31 men with prostate cancer scheduled for radical prostatectomy, 128 men scheduled for first diagnostic biopsy (prebiopsy cohort). , , and transcripts were detected by multiplex reverse transcription quantitative polymerase chain reaction, and the results were used for scores for calculation and statistical analysis.

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