Publications by authors named "Yuriy Khlopko"

Background And Aim: The cattle breeding system is facing severe problems associated with the increased negative impact of various human activity areas on the environment and the bodies of farm animals. The use of heavy metals in different production areas leads to their accumulation in the environment due to the ingestion of animals and humans through animal products. This study aimed to assess the elemental composition of the hair and milk of black-spotted cows and to identify the relationship between the content of toxic and essential elements and the state of the intestinal microbiome.

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The identification of new prognostic markers of renal cell carcinoma (RCC) is an urgent problem in oncourology. To investigate the potential prognostic significance of tumor microbiome and stromal inflammatory markers, we studied a cohort of 66 patients with RCC (23 clear cell RCC, 19 papillary RCC and 24 chromophobe RCC). The microbiome was analyzed in tumor and normal tissue by 16S rRNA amplicon sequencing.

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Article Synopsis
  • Corynebacterium amycolatum ICIS 99, isolated from healthy women's vaginal smears, demonstrated positive antimicrobial potential, prompting a genome analysis.
  • The draft genome is 2,532,503 bp long, containing 2186 coding sequences with a G + C content of 59.0%, and lacks true virulence factors.
  • It has genes that help it survive in the vaginal environment and produce beneficial metabolites, suggesting its potential as a safe probiotic strain; the genomic data is available in major databases.
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Article Synopsis
  • * Genome sequencing of three vaginal strains revealed their ability to produce metabolites that enhance the fighting power of beneficial bacteria against harmful microorganisms.
  • * These strains show genes that help them survive in the vaginal environment and have potential as probiotics to prevent pathogenic growth and support healthy colonization.
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The O-antigen (O-polysaccharide) is an essential component of lipopolysaccharide on the surface of Gram-negative bacteria and plays an important role in interaction with host organisms. In this study, we investigated the chemical structure and characterized the gene cluster of Enterobacter cloacae K7 O-antigen. As judged by sugar analyses along with NMR spectroscopy data, E.

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We report here the complete genome sequence of strain ICIS 96, which was isolated from the feces of a horse. Bacteriological characterization of strain ICIS 96 revealed the absence of pathogenicity factors, while its spectrum of antagonistic activity was found to be broad, having activities associated with both Gram-positive and Gram-negative bacteria. Analysis of the ICIS 96 genome revealed five genes associated with antimicrobial activity (enterocin [ent] A, ent B, lactobin A/cerein 7b, and ent L50 A/B).

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ICIS 9 was isolated from a vaginal smear of a healthy woman. Here, we report the draft genome sequence of ICIS 9, which will be useful for further studies of specific genetic features of this strain and for understanding its probiotic properties.

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This report describes the draft genome sequence of Corynebacterium amycolatum strain ICIS 53, isolated from the reproductive tract of a healthy woman. The size of the genome was 2,460,257 bp (58.98% G+C content).

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