Clinical usefulness of FDG-PET/CT for the evaluation of various types of adult T-cell leukemia.

Purpose: The aim was to explore undefined useful indices for clinically grading adult T-cell leukemia (ATL) using [F] 2-fluoro-2-deoxyglucose (FDG) - positron emission tomography/computed tomography (PET/CT).

Methods: A total of 28 patients with ATL (indolent, 9; aggressive, 19) were enrolled; all patients with aggressive ATL underwent FDG-PET/CT before chemotherapy. Patients with indolent ATL underwent FDG-PET/CT at the time of suspected disease progression and/or transformation; some received lymph node biopsy.