Publications by authors named "Yurii Samchenko"

This study presents an innovative approach to improve implant biointegration and reduce implant-associated infections using porous poly(vinyl formal) nanocomposite matrices incorporated with gold nanoparticles and antimicrobial/anticancer drugs for plastic surgery applications. The porous matrices were characterized using physicochemical techniques and in vitro biochemical assays. The results demonstrated the biocompatibility of PVF nanocomposites and their potential for functionalization with various bioactive molecules and drugs, thereby enhancing their therapeutic efficacy.

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Article Synopsis
  • Two types of hydrogels were created from acrylamide and copolymers with acrylonitrile and acrylic acid, using two different cross-linking methods: chemical (with N,N'-methylene bis-acrylamide) and physical (with montmorillonite).
  • Characterization of the gels was done using techniques like FTIR and SEM, showing notable structural differences depending on the cross-linking method.
  • The study found that gels with a specific composition (acrylamide-acrylic acid copolymer) were particularly pH sensitive and had the highest swelling capacity, alongside excellent sorption properties for cadmium(II) ions.
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The effects of acid activation of Laponite RD (Lap) on the structure and properties of activated Lap nanoparticles (aLap) and the properties of polyNIPAA hydrogels physically cross-linked by aLap have been studied. The acid activation of Lap by the sulfuric acid was done using the concentration of sulfuric acid within the interval = 0.525-14.

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Recently, considering the potential applications of hydrogel nanocomposites in biomedical engineering, there has been a growing interest in the synthesis of hydrogels with improved mechanical properties. Among magnetic materials, iron oxides are of particular interest due to their magnetic properties and biocompatibility. At the same time, LAPONITE®, a synthetic clay, can be used to improve the mechanical properties of polymer-based nanocomposites.

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