Publications by authors named "Yurii S Lazurkin"
J Biomol Struct Dyn
February 2004
Article Synopsis
- The study focuses on the formation of structurally isomeric complexes between homopyrimidine bis-PNAs and different forms of DNA (single- and double-stranded).
- Isomers S1, S2, and S3 are identified based on their mobility in polyacrylamide gel electrophoresis, with S3 being the most stable and forming exclusively on double-stranded DNA.
- The research also finds that the stability of isomer S1 significantly increases when an excess of complementary single-stranded oligonucleotide is present, and proposes that the S1 structure consists of two bis-PNA/DNA triplexes.
