Publications by authors named "Yuri Volpato Santos"
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Synopsis of recent research by authors named "Yuri Volpato Santos"
- Yuri Volpato Santos focuses on the allosteric regulation of protein kinase A (PKA) in trypanosomatid pathogens, particularly investigating the role of purine nucleosides in this process, which differs from the conventional cAMP-dependent mechanisms commonly observed in other eukaryotes
- His research demonstrates that the PKA in these protozoan organisms is independent of cyclic nucleotides, highlighting the discovery of 7-deaza-nucleosides as potent activators and high-affinity ligands for this unique form of PKA
- The findings have implications for understanding the signal transduction pathways in trypanosomatids, potentially contributing to the development of novel therapeutic targets against related diseases.
