Publications by authors named "Yuri Scheidegger de Castro"
Article Synopsis
- Leprosy is a chronic infection caused by the bacterium Mycobacterium leprae, which can lead to severe inflammatory reactions such as erythema nodosum leprosum (ENL) in 1 in 3 individuals, even those receiving treatment.
- Recent research indicates that co-infection with Toxoplasma gondii significantly increases the risk of these leprosy reactions, particularly ENL, with about 87.7% of patients with leprosy reactions testing positive for T. gondii.
- The study found that higher levels of IgE, a specific immunoglobulin, in patients co-infected with T. gondii may serve as a biomarker for predicting ENL episodes, suggesting
Serological evidence of Toxoplasma gondii infection as potential risk for the development of lepromatous leprosy in an endemic area for both neglected tropical diseases in Brazil.
Luciana Regina Pereira Oliveira Lívia Mattos Martins Rebeka da Conceição Souza Yuri Scheidegger de Castro Letícia Silva Nascimento
Infect Dis Poverty
February 2020
Background: Mycobacterium leprae and Toxoplasma gondii infections are both neglected tropical diseases highly prevalent in Brazil. Infection with certain parasite species can significantly alter susceptibility to other important pathogens, and/or influence the development of pathology. Here we investigated the possible influence of M.
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