Publications by authors named "Yuran Qian"

Objectives: This study aimed to quantitatively investigate the intractable 'roller coaster effect' (RCE) that occurs in premolar extraction cases treated with clear aligner therapy (CAT) or straight-wire appliance (SWA).

Methods: Protrusion cases treated with extraction of bilateral first premolars were included. Pre- and post-treatment cephalograms were obtained to measure the bending angle of occlusal plane (BAOP), namely the occlusal intersection angle between the anterior occlusal plane (AOP) and posterior occlusal plane (POP).

View Article and Find Full Text PDF

Background: The biological mechanisms driving orthodontic tooth movement (OTM) remain incompletely understood. Gingival crevicular fluid (GCF) is an important indicator of the periodontal bioprocess, providing valuable cues for probing the molecular mechanisms of OTM.

Methods: A rigorous review of the clinical studies over the past decade was conducted after registering the protocol with PROSPERO and adhering to inclusion criteria comprising human subjects, specified force magnitudes and force application modes.

View Article and Find Full Text PDF

Objectives: This study aims to establish an approach to integrate autonomous maximal smile (AMS) 3D facial image with digital 3D dental models to demonstrate the digital orthodontic set-up in the 3D facial context.

Methods: Using Geomagic Studio software, the AMS 3D facial image and pre-treatment dental model were manually and globally registered. Subsequently, the pre-treatment dental model was substituted with the predicted post-treatment dental model.

View Article and Find Full Text PDF

Background: Uncertainty exists regarding the pain scores and the success rate of intraligamentary anesthesia compared to other infiltration anesthesia. Based on the conditions of clinical anesthesia techniques, we conducted a systematic review and meta-analysis to compare the efficacy of intraligamentary anesthesia with other infiltration anesthesia.

Methods: The search was carried out in PubMed Central, Cochrane Central Register of Controlled Trials, MEDLINE (via OVID), Embase (via OVID), and Scopus from the inception to March 26, 2023.

View Article and Find Full Text PDF
Article Synopsis
  • Cancer cells grow uncontrollably and change their metabolism to support this growth, a process influenced by genes, growth factors, and interactions with surrounding cells.
  • The metabolic changes are complex and vary by tumor type and environment, often making tumors resistant to standard treatments.
  • Understanding these metabolic pathways can help develop new cancer therapies, and ongoing research is essential for uncovering how these metabolic alterations work and how to target them effectively.
View Article and Find Full Text PDF

Objective: Teriparatide (TPTD) and abaloparatide (ABL) are two osteoanabolic drugs targeting parathyroid hormone (PTH)1R signalling. This study aimed to investigate the effects of TPTD and ABL on the adolescent mandibular growth.

Method: In total, 70 4-week-old male Sprague-Dawley rats were randomly divided into 14 groups, treated with intermittent TPDT or ABL at various doses, accompanied by mandibular advancement (MA) or not.

View Article and Find Full Text PDF

Background: The aim of this study was to compare the effects of two osteoanabolic drugs, abaloparatide (ABL) and teriparatide (TPTD), on protecting alveolar bone in experimental periodontitis.

Methods: Twenty-four 9-week-old, male, Sprague-Dawley rats were placed with silk suture around the right maxillary second molar, and then were randomly divided into three groups, that is, the ABL, TPTD, and saline group, receiving intermittent subcutaneous injections of ABL (80 μg/kg), TPTD (80 μg/kg) or saline respectively every other day for 4 weeks. Samples on both sides were assessed through micro-computerized tomography, histological, and immunohistochemical analysis.

View Article and Find Full Text PDF

Background: Tumor-stroma ratio (TSR) is a promising new prognostic predictor for patients with rectal cancer (RC). Although several studies focused on this pathologic feature, results from those studies were still inconsistent.

Methods: This research aimed to estimate the prognostic values of TSR for RC.

View Article and Find Full Text PDF

Objectives: To determine whether the incorporation of N-acetylcysteine (NAC) improves the antibacterial ability and biocompatibility of nano silver (NAg)-containing orthodontic cement.

Materials And Methods: NAg was synthesized using a sodium citrate reduction method. NAg particles were characterized using transmission electron microscopy and ultraviolet-visible absorption spectra.

View Article and Find Full Text PDF