Glycyrrhizin alleviates radiation-induced lung injury by regulating the NLRP3 inflammasome through endoplasmic reticulum stress.

Objective: Radiation pneumonitis (RP) is the major adverse response of radiation therapy for thoracic malignant tumors, and there is a lack of effective interventions. The aim of this study was to investigate the radioprotective effect of Glycyrrhizin (GL) on RP and its potential mechanism.

Method: The body weight and lung weight of mice were monitored.

Thioridazine combined with carboplatin results in synergistic inhibition of triple negative breast cancer by targeting cancer stem cells.

Cancer stem cells (CSCs) in triple-negative breast cancer (TNBC) are closely related to tumorigenesis and metastasis. Thioridazine (THZ) is a usual phenothiazine antipsychotic drug that can destroy CSCs. We aimed to explore whether THZ could sensitize metastatic TNBC cells, especially the CSCs, to carboplatin (CBP) treatment.

Coordination environment evolution of Eu3+ during the dehydration and re-crystallization processes of Sm(1-x)Eu(x)[B9O13(OH)4]·H2O by photoluminescent characteristics.

There are limited photoluminescence (PL) studies for rare earth borates with crystalline water molecules, which are usually supposed to have low PL efficiency because the vibrations of H2O or -OH may lead to emission quenching. We investigated the PL properties of Sm(1-x)Eu(x)[B9O13(OH)4]·H2O (x = 0-1.00) and their dehydrated products α-Sm(1-x)Eu(x)B5O9.