Publications by authors named "Yuqianxun Wu"
Article Synopsis
- Large-scale genetic screenings have identified many cancer dependencies, but rare cancers are often overlooked, leaving their dependencies unclear.
- We conducted CRISPR knockout screens in translocation renal cell carcinoma (tRCC), uncovering new dependencies in mitochondrial function and kidney lineage pathways.
- Using machine learning, we predicted gene dependencies in other rare cancers like alveolar soft part sarcoma (ASPS) and explored data from a large tumor repository, identifying potential targets for treatment in several rare cancer types.
