Publications by authors named "Yuping Zhao"

The bioactive components of chrysanthemum tea are an essential indicator in evaluating its nutritive and commercial values. Combining hyperspectral imaging (HSI) with key wavelength selection and pattern recognition methods, this study developed a novel approach to estimating the content of bioactive components in chrysanthemums, including the total flavonoids (TFs) and chlorogenic acids (TCAs). To determine the informative wavelengths of hyperspectral images, we introduced a variable similarity regularization term into particle swarm optimization (denoted as VSPSO), which can focus on improving the combinatorial performance of key wavelengths and filtering out the features with higher collinearity simultaneously.

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Perovskite solar cells (PSCs) have achieved impressive efficiency, but their commercialization is limited by issues like chemical homogeneity within the perovskite films, leading to defects and phase segregation, which severely compromise the stability and performance of PSCs. This study presents a novel approach to overcoming these barriers by employing N,N-methylenebisacrylamide (MBA) as a multifunctional crosslinking agent within the perovskite structure. MBA enhances chemical uniformity both laterally and vertically, improves crystallinity, and boosts overall film stability by forming a robust crosslinked network that regulates nucleation and growth dynamics during the pre-seeding process.

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The increasing scarcity of water and soil resources, combined with inefficient water and fertilizer management, poses significant challenges to agriculture in arid regions. This study aimed to determine an optimal water and nitrogen regulation model to alleviate water shortages and improve agricultural productivity and quality. In this study, a two-year experiment was conducted to investigate the effects of varying irrigation and nitrogen levels on the soil environment and crop growth in a ||alfalfa system (LB||AS).

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Environmentally stable novel flexible bisperylene resorcin[4]arene molecular switch cavitand B and the corresponding rigid cavitand A were synthesized and a single crystal was obtained. Spectroscopic analysis revealed the formation of an excimer of perylene within the cavitand. The presence of flexible chains in cavitand B confers a high degree of environmental stability, rendering its fluorescence unaffected by external factors such as pH and temperature variations.

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The flowers of Hosta plantaginea (Lam.), a traditional Chinese medicine, is utilized for the treatment of sore throat, aphonia, and cough alleviation. The polysaccharides HPFP-1 and HPFP-2 were separated from these plants through water-soluble alcohol precipitation and column chromatography.

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Peroxynitrite (ONOO) is a bioactive molecule involved in various biochemical processes, and the abnormal concentration fluctuations of ONOO in living systems are closely associated with various diseases, including cancer. An important characteristic of the tumor microenvironment is the overexpression of ONOO, highlighting the significance of specific detection of ONOO in distinguishing between tumor tissue and normal tissue. A single near-infrared second window (NIR-II) molecular probe integrated fluorescence imaging and photothermal therapy can achieve precise localization and effective ablation of deep-seated tumor tissue.

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  • * Results showed that higher occurrence of EEG microstate class B was linked to a greater likelihood of non-remission from psychiatric symptoms and correlated with more severe symptoms at onset.
  • * These findings suggest microstate class B could be used as a potential biomarker for assessing the severity and prognostic evaluation of ORPS in patients.
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  • Hereditary spherocytosis (HS) is an inherited form of hemolytic anemia caused by defects in erythrocyte membrane proteins, leading to symptoms like spherocytes in blood, anemia, enlarged spleen, jaundice, and gallstones.
  • Genetic testing has become essential for diagnosing HS, with pathogenic variations found in five specific genes (ANK1, SPTA1, SPTB, SLC4A1, EPB42).
  • In a study of 41 patients, various pathogenic mutations were identified, with significant differences in platelet and LDH levels between patients with different gene mutations, particularly lower levels in those with SPTB and SLC4A1 mutations compared to ANK1
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  • Understanding how ferroptosis works can help in diagnosing and treating diseases, but researchers have struggled to measure changes in cell membrane tension during this process.
  • This study introduces new mechanosensitive fluorescence lifetime probes that allow for simultaneous imaging of both the plasma membrane and the nuclear envelope, providing valuable insights into ferroptosis dynamics.
  • The findings show that membrane tension decreases in both membranes during ferroptosis, with the nuclear envelope undergoing budding in later stages, and membrane damages are repaired in low-tension areas through a process called exocytosis.
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Moxa wool (MW), derived from the dried leaves of , plays a significant role in traditional Chinese medicine. However, the quality of MW varies with its storage period, impacting its therapeutic efficacy. Traditional methods for quality detection are limited and destructive.

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  • The latest advancement in perovskite solar cell (PSC) technology focuses on a new technique called thermal imprinting-assisted ion exchange passivation (TIAIEP) that targets surface defects.
  • TIAIEP enhances the performance of PSCs by using a passivator to promote ion exchange specifically at defect sites, creating a compositional gradient that minimizes charge recombination.
  • Devices treated with TIAIEP achieve a power conversion efficiency of 22.29% and display impressive longevity, retaining 91% efficiency after 2000 hours of storage and 90% after 1200 hours of continuous light exposure.
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The economical and efficient commercial production of second-generation bioethanol requires fermentation microorganisms capable of entirely and rapidly utilizing all sugars in lignocellulosic hydrolysates. In this study, we developed a recombinant strain, BLH510, through protoplast fusion and metabolic engineering to enhance its ability to co-ferment glucose, xylose, cellobiose, and xylooligosaccharides while tolerating various inhibitors commonly found in lignocellulosic hydrolysates. The parental strains, LF1 and BLN26, were selected for their superior glucose/xylose co-fermentation capabilities and inhibitor tolerance, respectively.

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Hepatic metachronous oligometastatic nasopharyngeal carcinoma (hmoNPC) exhibits distinct clinical characteristics compared to other types of metastatic NPC. We investigated the optimal therapy for hmoNPC. 160 patients with hmoNPC treated in Sun Yat-sen University Cancer Center between 2010 and 2021 were retrospectively recruited.

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  • The review studies how minerals are added inside tiny structures in teeth (dentin) and talks about the use of special substances called ACP stabilizers.
  • Researchers looked through many online articles to find out how these ACP stabilizers help teeth remineralize and what challenges exist in using them in real-life treatments.
  • The findings show that different stabilizers, like proteins and polymers, help ACP in remineralization, but there are still problems in creating effective dental products that work well.
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Purpose: To determine the prevalence of anxiety and depression in patients with nasopharyngeal carcinoma (NPC) and to identify central symptoms and bridge symptoms among psychiatric disorders.

Methods: This cross-sectional study recruited patients with NPC in Guangzhou, China from May 2022, to October 2022. The General Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9) were used for screening anxiety and depression, respectively.

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Objective: Comorbid depression and anxiety in patients with epilepsy (PWE) are common and frequently under-treated, thus, causing poor health-related quality of life (HRQoL). However, little is known regarding the interconnections between anxious/depressive symptoms and the dimensions of HRQoL. Therefore, we conducted a network analysis to explore these relationships in detail among Chinese adult PWE.

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  • The study investigates immune persistence after switching from trivalent oral poliovirus vaccine (tOPV) to a new immunization schedule (IPV and bOPV) since 2016.
  • Blood samples were collected from 1104 participants at various ages to measure antibody levels against polioviruses.
  • Results showed that while type 1 and type 3 antibody rates were similar across groups, the 2-specific antibody rates were much higher in the IPV-IPV-tOPV group compared to others, indicating some schedules did not effectively maintain immunity against poliovirus type 2.
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  • This study investigates the effects of Pueraria lobata (PL) water extract (PLE) on treating myocardial infarction (MI) by using advanced analytical techniques to analyze its chemical composition and therapeutic potential.
  • It employs a combination of targeted metabolomics and genomic sequencing to examine PLE's impact on cardiac health and intestinal flora in a rat model of MI.
  • The results indicate that PLE significantly reduces cardiac injury and enhances levels of key amino acids and enzymes involved in metabolism, while also restoring balance to the intestinal microbiome in MI rats.
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  • Topical photodynamic therapy (PDT) using 5-aminolevulinic acid (5-ALA) shows promising results for treating oral leukoplakia (OLK) among Chinese patients, with a 68% overall response rate observed in a study of 50 patients.
  • The study found that while PDT can lead to improvements, 52% of patients experienced side effects such as oral pain and ulcers, especially those with more severe forms of OLK.
  • Follow-up revealed a 32% recurrence rate of hyperplasia and dysplastic lesions, and lesions on the buccal mucosa were associated with lower recurrence rates, indicating the treatment's effectiveness and potential risk factors.
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  • - Combining deep learning with hyperspectral imaging (HSI) enhances quality control for medicinal and edible plants, but hyperspectral data can have redundant information, complicating sample identification.
  • - An enhanced one-dimensional convolutional neural network (1DCNN) with attention mechanisms improves feature recognition by focusing on relevant data while filtering out irrelevant information.
  • - The study shows that this attention-enhanced model significantly outperforms traditional machine learning methods, achieving up to 99.35% accuracy in classifying plant species, demonstrating its reliability and efficiency in quality control applications.
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Yeast protein concentrate, a by-product of the fermentation industry waste, is a potential alternative protein source with high nutritional quality, environmental sustainability, and functional properties. However, its digestibility and digestion behavior are poorly understood. In this study, we compared the in vitro digestion behavior of yeast protein concentrate and whey protein concentrate using simulated gastrointestinal conditions.

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  • Gallic acid, a natural green additive in food production, negatively affects the growth and metabolism of Escherichia coli, limiting its production efficiency.
  • Research on E. coli W3110 ATCC (82057) under gallic acid stress revealed a significant decrease in cell biomass and irregular cell shapes.
  • Transcriptome analysis identified several strategies E. coli employs to adapt, including reducing absorption of gallic acid, enhancing its excretion through upregulated efflux systems, and maintaining internal stability in acidic conditions.
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The controllable character of the melting point of deep eutectic solvents (DESs) makes it easy to realize lubricated state transitions and produce excellent lubricating properties during friction. In this work, a series of novel imidazole-based DESs were synthesized to present a room-temperature solid state by shifting its eutectic point. Tribological test results show that the wear volume of these DESs decreases as the alkyl chains of the hydrogen bond donors increase.

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  • Puerariae Lobatae Radix is a traditional Chinese medicine known for its roots, but it is often sold mixed with a less desirable plant part (Puerariae Lobatae Caulis), causing quality concerns.
  • The study utilized hyperspectral imaging (HSI) with various lenses to accurately differentiate between these two products, employing advanced analytical methods like multi-layer perceptron (MLP), partial least squares discriminant analysis (PLS-DA), and support vector machine (SVM).
  • The MLP model proved to be the most accurate, achieving up to 99.11% accuracy, with a final recommendation to use specific wavelengths (2,100-2,400 nm) for developing quick, non-des
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Objective: To investigate the risk factors associated with lower extremity deep vein thrombosis (LEDVT) and to establish a predictive model for patients who undergo gynecologic laparoscopic surgery.

Methods: A review of clinical data was conducted on patients who underwent gynecologic laparoscopic surgery between November 1, 2020, and January 31, 2022. Patients who developed LEDVT after surgery were included as the observation group, while the control group comprised patients who did not experience complications.

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