Publications by authors named "Yupeng Pei"
The purpose of this network meta-analysis (NMA) was to compare the therapeutic effects of various Danshen ( Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma]) injections on heart failure to determine the optimal Danshen injection combined with conventional treatment. 8 databases were searched from the inception of these databases to May 2023 to collect randomized controlled trials (RCTs) on the effectiveness and safety of Danshen injections in the treatment of heart failure. This NMA was performed using Stata 16.
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- Kluyveromyces marxianus, a yeast strain, shows promise for producing yeast extracts due to its effective fermentation and nutritional features.
- The study investigates the process of yeast autolysis, which is critical for extract production, and reveals that vacuum negative pressure and higher temperatures trigger this breakdown, but the molecular mechanisms are not yet fully understood.
- RNA-seq analysis identified numerous differentially expressed genes related to RNA synthesis and protein translation during autolysis, indicating that stress leads to cell damage through activated pathways like ERAD and autophagy, ultimately contributing to yeast cell autolysis.
Yeast autolysis refers to the process in which cells degrade and release intracellular contents under specific conditions by endogenous enzymes such as proteases, nucleases and lipid enzymes. Protein-rich baker's yeast is widely used to produce yeast extract in food industry, however, the molecular mechanism related to baker's yeast autolysis is still unclear. In this study, RNA-seq technology and biochemical analysis were performed to analyze the autolysis processes in baker's yeast.
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