Nuclear speckles are nuclear membraneless organelles in higher eukaryotic cells playing a vital role in gene expression. Using an in situ reverse transcription-based sequencing method, we study nuclear speckle-associated human transcripts. Our data indicate the existence of three gene groups whose transcripts demonstrate different speckle localization properties: stably enriched in nuclear speckles, transiently enriched in speckles at the pre-messenger RNA stage, and not enriched.
View Article and Find Full Text PDFAt present, phosphor-in-glass is regarded as a superior encapsulation material substituting for organic materials to resolve the poor thermal stability of WLEDs. However, the serious erosion reaction between commercial red phosphor and the glass matrix restricts the development and application of red phosphor-in-glass. In this work, a novel SrAlO:Li,Mn (SAO) red phosphor-in-glass film (PiGF) with precursor glass BO-(85 - )BiO-5AlO-10CaO was prepared using a low-temperature sintering technique.
View Article and Find Full Text PDFNuclear speckles, a type of membraneless nuclear organelle in higher eukaryotic cells, play a vital role in gene expression regulation. Using the reverse transcription-based RNA-binding protein binding sites sequencing (ARTR-seq) method, we study human transcripts associated with nuclear speckles. We identify three gene groups whose transcripts demonstrate different speckle localization properties and dynamics: stably enriched in nuclear speckles, transiently enriched in speckles at the pre-mRNA stage, and not enriched in speckles.
View Article and Find Full Text PDFThe absence of high-efficiency oxide red phosphors restricts the development of high-performance solid-state lighting. In this work, a series of Li doped SrAlO:Mn (SAO-Li) red phosphors were prepared. Theoretical calculation results indicate that Li is inclined to occupy the gap 2 position.
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