RIPK1 plays a crucial role in maintaining regulatory T-Cell homeostasis by inhibiting both RIPK3- and FADD-mediated cell death.

Regulatory T (T) cells play an essential role in maintaining immune balance across various physiological and pathological conditions. However, the mechanisms underlying T homeostasis remain incompletely understood. Here, we report that RIPK1 is crucial for T cell survival and homeostasis.

Host-guest type multiple site fluorescent probe for GSH detection in living organisms.

The host-guest type molecular size matching strategy, which embodied intramolecular hydrogen bond, aromatic nucleophilic substitution and nucleophilic addition, was utilized to develop a fluorescent probe for GSH specific detection and imaging in organisms.