Publications by authors named "Yunyu Wu"

The genetic improvement of rice eating and cooking quality (ECQ) is an important goal in rice breeding. It is important to understand the genetic regulation of ECQ at the genomic level for effective breeding to improve ECQ. However, the mechanisms underlying the improvement of ECQ of indica and japonica cultivars in southern China remain unclear.

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Objectives: Owing to differences in cultural background, education level, and lifestyle, certain items of existing tinnitus evaluation scales are difficult for Chinese patients to understand, despite being translated. However, few independently developed scales have been developed specifically for Chinese patients. Therefore, with this study, we aimed to construct a tinnitus scale, the West China Tinnitus Impact Inventory (WCTII), suitable for the accurate reflection of the impact and severity of the disease in this population.

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Aqueous zinc ion batteries (AZIBs) have received a lot of attention in electrochemical energy storage systems for their low cost, environmental compatibility, and good safety. However, cathode materials still face poor material stability and conductivity, which cause poor reversibility and poor rate performance in AZIBs. Herein, a heterogeneous structure combined with cation pre-intercalation strategies was used to prepare a novel CaVO·3HO@NiVO·nHO material (CaNiVO) for high-performance Zn storage.

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Top managers' past experiences (e.g., foreign experience) significantly impact their decision-making behavior, which may influence firms' sustainable development.

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Understanding the environmental response patterns of riverine microbiota is essential for predicting the potential impact of future environmental change on river ecosystems. Vulnerable plateau ecosystems are particularly sensitive to climate and local environmental changes, however, the environmental response patterns of the taxonomic and functional diversity of riverine microbiota remain unclear. Here, we conducted a systematic investigation of the taxonomic and functional diversity of bacteria and archaea from riparian soils, sediments, and water across the elevation of 1800- 4800 m in the Qinghai-Tibet Plateau rivers.

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Background: As a small G protein of Ras family, Ras-like-without-CAAX-1 (RIT1) plays a critical role in various tumors. Our previous study has demonstrated the involvement of RIT1 in promoting malignant progression of hepatocellular carcinoma (HCC). However, its underlying mechanism remains unclear.

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Rice blast, caused by the fungal pathogen Magnaporthe oryzae, is one of the most important diseases of rice. Utilization of blast-resistance genes is the most economical, effective, and environmentally friendly way to control the disease. However, genetic resources with broad-spectrum resistance (BSR) that is effective throughout the rice growth period are rare.

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This study reports the creation of herbicide-resistant rice lines via CRISPR-Cas9-mediated editing of the 3' UTR of OsHPPD. Resistance index calculations revealed that two resistant lines, TS8-2-10 and TS8-8-6, exhibited 4.8-fold and 3.

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The existing literature on corporate social responsibility (CSR) drivers focuses on firm- and institution-level factors and rarely on the role of political incentives. Public officials control enormous resources in China, and their political incentives substantially shape certain firm behaviors. As CSR is one of the critical measures that the central government uses to evaluate the performance of local government, local officials have the incentive to channel firms into accomplishing their political goals.

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Rice blast, caused by (), is one of the most destructive diseases threatening rice production worldwide. Development of resistant cultivars using broad-spectrum resistance () genes with high breeding value is the most effective and economical approach to control this disease. In this study, the breeding potential of gene in / rice breeding practice in Jiangsu province was comprehensively evaluated.

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Increasing rice yield is essential for alleviating global food crisis. High soil nutrient level guarantees high rice yields in conventional rice monoculture (RM) systems, but excessive unconsumed nutrients act as pollutants and can even threaten rice growth. The integrated rice-crayfish (IRC) system aims to transfer the excess nutrients from crayfish to paddy fields to improve the comprehensive utilization rate of nutrients and create additional profits, while the responding characteristics of IRC microbial communities in paddy fields and rice yields to the nutrient status remain unclear.

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The amyloplast is a specialized plastid in rice endosperm cells where starch is synthesized and stored as starch granules (SGs). However, little is known about the molecular mechanism underlying amyloplast and SG development. In this study, a novel mutant (c134) demonstrating a floury endosperm with enlarged SGs and amyloplasts was identified.

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Unlabelled: Rice blast is one of the most widespread and devastating diseases in rice production. Tremendous success has been achieved in the identification and characterization of genes and quantitative trait loci (QTLs) conferring seedling blast resistance, however, genetic studies on panicle blast resistance have lagged far behind. In this study, two advanced backcross inbred sister lines (MSJ13 and MSJ18) were obtained in the process of introducing into C134S and showed significant differences in the panicle blast resistance.

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Article Synopsis
  • Balancing yield, quality, and disease resistance in crop breeding is challenging due to their negative interactions, particularly in japonica rice production in Central China, where many high-yield varieties suffer from poor quality or disease vulnerability.
  • Researchers re-sequenced 200 japonica rice varieties and performed genomic analyses using millions of SNP markers, revealing that a focus on yield and taste quality has led to reduced resistance to rice blast disease.
  • The study successfully introduced superior traits for taste quality and blast resistance into two high-yield rice lines, demonstrating a genomic strategy that balances multiple agronomic traits for better rice varieties.
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Study Objective: The purpose of this feasibility study is to develop and validate a new assessment tool and scoring system for multitasking competency for physicians in-training in a timed simulated setting. The multitasking competency includes ability to appropriately prioritize and implement tasks for different patients who present simultaneously.

Methods: We designed three single task stations with different levels of difficulty and priority.

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Article Synopsis
  • A systematic review and meta-analysis aimed to evaluate the diagnostic accuracy of ultrasound for small bowel obstruction (SBO), with previous studies showing varied sensitivity (82%-100%) and specificity (54%-100%).
  • The analysis included 15 studies, finding pooled sensitivity at 92% and specificity at 93%, although specificity was notably lower in North America and emergency settings, where CT was the sole reference standard.
  • While ultrasound is generally reliable for diagnosing SBO, practitioners should be cautious due to variability in specificity depending on the study context and diagnostic methods used.
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BACKGROUND This study aimed to identify important marker genes in lung adenocarcinoma (LACC) and establish a prognostic risk model to predict the risk of LACC in patients. MATERIAL AND METHODS Gene expression and methylation profiles for LACC and clinical information about cases were downloaded from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, respectively. Differentially expressed genes (DEGs) and differentially methylated genes (DMGs) between cancer and control groups were selected through meta-analysis.

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Objective: MicroRNAs (MiRNAs) is thought to play a critical role in the initiation and progress of ovarian cancer (OC). Although miRNAs has been widely recognized in ovarian cancer, the role of hsa-miR-30a-5p (miR-30a) in OC has not been fully elucidated.

Methods: Three mRNA datasets of normal ovarian tissue and OC, GSE18520,GSE14407 and GSE36668, were downloaded from Gene Expression Omnibus (GEO) to find the differentially expressed gene (DEG).

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Currently, more and more studies show that aberrantly expressed microRNAs (miRNAs) are important driving factors for the pathogenesis of hepatocellular carcinoma (HCC). Based on the TCGA and GEO databases, miR-660-5p was identified as a possible target for HCC in this study.In HCC tissues, miR-660-5pexpressionwasparticularly high, and this was confirmed inHCC cell lines.

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Background: Ovarian cancer is usually not diagnosed until the late stage, and it is resistant to platinum and other standard chemotherapy drugs, resulting in high mortality.

Objectives: To investigate the effects of miR-140-5p on cell proliferation, apoptosis, invasion, and migration capability in the SKOV3 and OVCAR3 ovarian cancer cell lines through Wnt signaling pathway.

Material And Methods: Expression levels of miR-140-5p were checked using quantitative real-time polymerase chain reaction (qRT-PCR).

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Article Synopsis
  • The research focuses on analyzing genomic and phenotypic data from a diverse collection of 1,275 rice accessions, primarily consisting of popular Chinese rice cultivars and hybrid lines.
  • The collection is categorized into three indica and three japonica subgroups that reflect their geographic and breeding origins, with extensive phenotypic data covering 29 agronomic traits collected across various environments.
  • Through genome-wide association studies (GWAS), the study identifies 143 significant genetic loci related to important traits such as heading date and amylose content, highlighting underutilized favorable alleles that could enhance future rice breeding.
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Purpose: Serum complement C3 has been shown to contribute to the incidence of type 2 diabetes (T2D), but how serum complement C3 affects islet β-cell function throughout the course of T2D is unclear. This study explored whether serum complement C3 is independently associated with changes in islet β-cell function over time in patients with T2D.

Methods: Serum complement C3 was measured, and endogenous β-cell function was evaluated by area under the C-peptide curve (AUC) during an oral glucose tolerance test (OGTT) in 411 patients with T2D at baseline from 2011 to 2015.

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Background: Broad-spectrum resistance gene pyramiding helps the development of varieties with broad-spectrum and durable resistance to M. oryzae. However, detailed information about how these different sources of broad-spectrum resistance genes act together or what are the best combinations to achieve broad-spectrum and durable resistance is limited.

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