, , and are, respectively, typical arboreal, shrubby, and herbaceous species in oases of arid regions. It is important to study the difference in metabolic characteristics of the rhizosphere fungal community of these plant species and their relationships with soil factors for the preservation of delicate arid oasis ecosystems with future environmental changes. In this study, we, respectively, collected 18 rhizosphere soil samples of , .
View Article and Find Full Text PDFDepression is a prevalent mental illness, affecting a significant portion of the global population. Recent research has highlighted the crucial role of the gut microbiota in both metabolic and central nervous health. By reviewing literature from various databases, including Pubmed, Science Direct, Web of Science, and Scopus, spanning the years 2005-2023, a comprehensive search was conducted using keywords such as "Depression" and "Gut Microbiota".
View Article and Find Full Text PDFRecently, the underlying mechanisms of acupuncture on the effects of Alzheimer's disease (AD) treatment have not been fully elucidated. Defects in ALP (autophagy-lysosomal pathway) and TFEB (transcription factor EB) play critical roles in AD. Our previous studies have demonstrated that electroacupuncture (EA) can ameliorate both β-amyloid (Aβ) pathology and cognitive function in APP/PS1 mice.
View Article and Find Full Text PDFObjective: To explore the mechanism of electroacupuncture(EA) in improving learning-memory ability in Alzheimer's disease (AD) mice from the perspective of endosomal-lysosomal system.
Methods: Male APP/PS1 transgenic mice were randomly divided into model group and EA group (=10 in each group) and 10 male C57BL/6 wild mice were taken as the normal group. EA (1 Hz/50 Hz, 1 mA) was applied at bilateral "Yongquan"(KI1) and acupuncture was applied at "Baihui" (GV20) for 15 min.
Objective: To investigate the effect of electroacupuncture (EA) on the expression of β-amyloid (Aβ) and autophagy-related proteins in hippocampal cells of Alzheimer's disease (AD) model mice, so as to explore its underlying mechanisms.
Methods: Eighteen male APP/PS1 transgenic mice (6 months old) were randomly divided into model and EA groups, with 9 mice in each group. Nine male C57BL/6 wild-type mice of the same age were chosen as the normal group.