Rucaparip (Rubraca) induces necrosis via upregulating the expression of RIP1 and RIP3 in ovarian cancer cells.

In the current study we investigated the inhibitory effect of rucaparib (Rubraca) on human ovarian cancer SKOV3 and A2780 cells and its possible mechanism. Cancer cells and human normal ovarian epithelial IOSE80 cells were treated with Rubraca at different concentrations. Cell viability was measured by MTT assay.

Seasonal dynamics of total flavonoid contents and antioxidant activity of Dryopteris erythrosora.

The seasonal dynamics of the total flavonoid contents in various parts of Dryopteris erythrosora, a traditional Chinese medicinal fern, and their antioxidant activity were investigated. The total flavonoids content in various parts of D. erythrosora showed an obvious seasonal dynamic change.