Publications by authors named "Yunwan Jeon"
Context: The effect of baseline (B) and alteration of metabolic parameters (MPs), including plasma glucose (PG) testing, insulin resistance surrogates, and lipid profile and their mutual interactions on the development of type 2 diabetes mellitus (T2DM), has not been investigated systematically.
Objective: To access the association of the past variability (V), past mean (M), and B values of various MPs and their mutual interaction with the risk of T2DM.
Methods: A community-based, longitudinal analysis was conducted using the Korean Genome and Epidemiology Study comprising 3829 nondiabetic participants with completed MPs measurements during 3 biannually visits who were followed over the next 10 years.
Article Synopsis
- The study assesses whether averaging fasting, 1-hour, and 2-hour plasma glucose levels offers a superior prediction for the future risk of type 2 diabetes (T2DM).
- Over 12 years, data from 7,533 participants were analyzed, showing that the averaged glucose index (GLU) had better hazard ratios and area under the curve metrics than individual glucose measurements.
- The conclusion is that using the mean of these different glucose values is more effective in predicting future T2DM compared to evaluating each glucose measurement separately.