Publications by authors named "Yunus E Bayrak"
Background: Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome is a recurrent fever syndrome. The exact etiopathogenesis of PFAPA syndrome remains unknown. Biological fluids or tissues may provide disease-specific biomarkers that may help clinicians to find new pathogenic pathways.
View Article and Find Full Text PDFObjective: This study investigated the utility of low-dose CT (ldCT) compared with MRI in diagnosing sacroiliitis in enthesitis-related arthritis (ERA) patients.
Methods: Thirty patients diagnosed with ERA were evaluated, with a median follow-up of 1.47 years.
Article Synopsis
- Behçet's disease (BD) is a systemic condition that can affect children and may lead to serious cardiovascular issues, like early atherosclerosis, due to ongoing inflammation.
- This study compared 30 children with juvenile BD to 20 healthy controls, measuring their epicardial adipose tissue (EAT) and carotid intima-media thickness (CIMT), finding that EAT was significantly thicker in BD patients, while CIMT did not show notable differences.
- The findings suggest that increased EAT thickness could indicate a risk for early atherosclerosis in children with BD, highlighting the need for further research to explore screening for these risks in larger groups.
Objective: Postural orthostatic tachycardia syndrome (POTS) is one of the orthostatic intolerance syndromes that are common in young adolescents and impair quality of life. POTS is a multi-systemic disease. Many mechanisms have been defined in POTS etiology, such as autonomic denervation, hypovolemia, hyperadrenergic stimulation, low condition, and hypervigilance.
View Article and Find Full Text PDFBackground: The present study aims to evaluate possible cardiac involvement in juvenile dermatomyositis (JDM) patients by conventional methods and cardiac magnetic resonance imaging (MRI) along with a systematic review of the literature on cardiac features in JDM.
Methods: The study group consisted of JDM patients who underwent cardiac MRI. We conducted a systematic review of the published literature involving JDM patients with cardiac involvement.
Purpose: This cross-sectional optical coherence tomography angiography (OCTA) study aimed to assess the macular and optic nerve head (ONH) vascular density, foveal avascular zone, and outer retina and choriocapillaris flow in oligoarticular juvenile idiopathic arthritis (oJIA).
Study Design: Prospective.
Methods: Twenty-two eyes of 22 oJIA patients with uveitis (oJIA-U), 20 eyes of 20 oJIA patients without uveitis (isolated oJIA), and 26 healthy volunteers of similar ages and sexes were investigated.
Objectives: Chronic diseases impact people's quality of life (QoL). Behçet's disease (BD) is a multisystemic chronic disease characterized by vasculitis of various vessels. We aimed to assess QoL in paediatric BD (PEDBD) patients and their parents.
View Article and Find Full Text PDFBackground: Atherosclerotic changes can be attributed to early endothelial damage in individuals with hypertension. We aimed to explore the relationship between endothelial dysfunction and hypertension in newly diagnosed children without end-organ damage, considering carotid intima-media thickness (CIMT), flow-mediated dilatation (FMD), and functional capillaroscopy parameters. We also analyzed the differences between dipper and non-dipper patients.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the need for better biomarkers to assess the risk of uveitis in patients with oligoarticular juvenile idiopathic arthritis (oJIA), as current methods are limited.
- Tear samples from both oJIA patients without uveitis and those with uveitis were analyzed using advanced protein identification techniques.
- The analysis found that out of 15 common proteins identified, 10 were upregulated and 2 downregulated in uveitis patients, with cystatin-S showing the highest increase, indicating its potential as a key biomarker.