Effects of COVID-19 safety protocols on health workers' quality of life; the mediating role of mental health and physical health; a retrospective study.

This study conducts an empirical retrospective examination of the effect of COVID-19 protocols on Health workers' quality of life during the pandemic. Data from a survey respondent of 330 health workers were analyzed through structural equation modeling. Results indicated COVID-19 protocols specifically hand hygiene, personal protective equipments, and physical distancing had a significant effect on the quality of life of health workers during the COVID-19 era.

Nano-Assembled Polyphosphazene Delivery System Enables Effective Intranasal Immunization with Nipah Virus Subunit Vaccine.

The ultimate vaccine against infections caused by Nipah virus should be capable of providing protection at the respiratory tract─the most probable port of entry for this pathogen. Intranasally delivered vaccines, which target nasal-associated lymphoid tissue and induce both systemic and mucosal immunity, are attractive candidates for enabling effective vaccination against this lethal disease. Herein, the water-soluble polyphosphazene delivery vehicle assembles into nanoscale supramolecular constructs with the soluble extracellular portion of the Hendra virus attachment glycoprotein─a promising subunit vaccine antigen against both Nipah and Hendra viruses.

The Effect of Composition on the Properties and Application of CuO-NiO Nanocomposites Synthesized Using a Saponin-Green/Microwave-Assisted Hydrothermal Method.

In this study, we explored the formation of CuO nanoparticles, NiO nanoflakes, and CuO-NiO nanocomposites using saponin extract and a microwave-assisted hydrothermal method. Five green synthetic samples were prepared using aqueous saponin extract and a microwave-assisted hydrothermal procedure at 200 °C for 30 min. The samples were pristine copper oxide (100C), 75% copper oxide-25% nickel oxide (75C25N), 50% copper oxide-50% nickel oxide (50C50N), 25% copper oxide-75% nickel oxide (25C75N), and pristine nickel oxide (100N).

Methods for identification of the opportunistic gut mycobiome from colorectal adenocarcinoma biopsy tissues.

Colorectal cancer poses a significant threat to global health, necessitating the development of effective early detection techniques. However, the potential of the fungal microbiome as a putative biomarker for the detection of colorectal adenocarcinoma has not been extensively explored. We analyzed the viability of implementing the fungal mycobiome for this purpose.

Analyzing gully erosion and deposition patterns in loess tableland: Insights from small baseline subset interferometric synthetic aperture radar (SBAS InSAR).

The fragile Loess Plateau of China suffers substantial gully erosion. It is imperative to elucidate gully erosion patterns for implementing effective erosion control strategies. However, high spatiotemporal resolution quantification of gully dynamics remains limited across the Loess Plateau landscape.

Surgical aortic valve replacement etiologies, hemodynamics, and outcomes in 1346 patients from the Malaysian heart centre.

Background: This study examined the characteristics and outcomes of surgical aortic valve replacement (SAVR) both isolated and in combination with other cardiac surgery in Malaysia from 2015 to 2021.

Methods: This was a retrospective study of 1346 patients analyzed on the basis of medical records, echocardiograms and surgical reports. The overall sample was both considered as a whole and divided into aortic stenosis (AS)/aortic regurgitation (AR)-predominant and similar-severity subgroups.

Ribosomal protein L8 regulates the expression and splicing pattern of genes associated with cancer-related pathways.

Background/aim: Ribosomal proteins have been shown to perform unique extraribosomal functions in cell apoptosis and other biological processes. Ribosomal protein L8 (RPL8) not only has important nonribosomal regulatory functions but also participates in the oncogenesis and development of tumors. However, the specific biological functions and pathways involved in this process are still unknown.

[Advances in the application of prosthetic reconstruction after tumor resection of the distal tibia:a systematic review].

The limited coverage of soft tissue and complex biomechanical factors make resection and reconstruction of distal tibial tumors extremely challenging. Megaprosthesis can provide good mechanical strength for tumor en bloc resection, but there are many postoperative complications, and the problems of insufficient soft tissue coverage and postoperative ankle instability must be solved. The development of three-dimensional digital technology may provide a new treatment strategy for distal tibial reconstruction.

Turbidity dynamics in Indian peninsular river mouths derived from K490 reveals key anthropogenic drivers.

Large rivers, which act as natural integrators of surface processes, contribute massive volume of terrestrial materials to the coastal oceans. However, the accelerated climate warming and increasing anthropogenic activities recorded in recent years have been severely affecting the hydrologic and physical regimes of river systems. These changes have a direct impact on river discharge and runoff, some of which are occurred rapidly in the past two decades.

Retraction Note: Weather indicators and improving air quality in association with COVID-19 pandemic in India.

[This retracts the article DOI: 10.1007/s00500-021-06012-9.].

Earthquake-induced soil landslides: volume estimates and uncertainties with the existing scaling exponents.

Quantifying landslide volumes in earthquake affected areas is critical to understand the orogenic processes and their surface effects at different spatio-temporal scales. Here, we build an accurate scaling relationship to estimate the volume of shallow soil landslides based on 1 m pre- and post-event LiDAR elevation models. On compiling an inventory of 1719 landslides for 2018 M 6.

Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge.

Ebolavirus (EBOV) infection in humans is a severe and often fatal disease, which demands effective interventional strategies for its prevention and treatment. The available vaccines, which are authorized under exceptional circumstances, use viral vector platforms and have serious disadvantages, such as difficulties in adapting to new virus variants, reliance on cold chain supply networks, and administration by hypodermic injection. Microneedle (MN) patches, which are made of an array of micron-scale, solid needles that painlessly penetrate into the upper layers of the skin and dissolve to deliver vaccines intradermally, simplify vaccination and can thereby increase vaccine access, especially in resource-constrained or emergency settings.

Mathematical analysis of fractional-order Caputo's derivative of coronavirus disease model via Laplace Adomian decomposition method.

Background: The world's survival ability has been threatened by the COVID-19 outbreak. The possibility of the virus reemerging in the future should not be disregarded, even if it has been confined to certain areas of the world after wreaking such havoc. This is because it is impossible to prove that the virus has been totally eliminated.

Quantifying spatio-temporal variation in aquaculture production areas in Satkhira, Bangladesh using geospatial and social survey.

Despite Bangladesh being one of the leading countries in aquaculture food production worldwide, there is a considerable lack of updated scientific information about aquaculture activities in remote sites, making it difficult to manage sustainably. This study explored the use of geospatial and field data to monitor spatio-temporal changes in aquaculture production sites in the Satkhira district from 2017-2019. We used Shuttle Radar Topographic Mission digital elevation model (SRTM DEM) to locate aquaculture ponds based on the terrain elevation and slope.

Circadian rhythm shifts and alcohol access in adolescence synergistically increase alcohol preference and intake in adulthood in male C57BL/6 mice.

Background: Adolescents have a natural tendency to be night owls, maintaining delayed circadian rhythms, and this rhythm is in direct conflict with the early wake times required during the school year. This leads to 'social jetlag', chronic circadian stress or desynchrony (CD) in which the rhythm of the intrinsic body clock is out of sync with behavior. CD increases alcohol intake in adolescents and adults, yet it is unknown whether adolescent CD also increases long-term addiction risk.

Farmer's knowledge and suggested approaches for controlling aflatoxin contamination of raw milk in Pakistan.

Monitoring of aflatoxin levels in milk is often complicated in developing countries due to the dominance of informal markets channeling milk in raw form. Farmer's awareness and voluntary participation in aflatoxin mitigation can be critical in such scenarios. Therefore, the present study was conducted to understand the perceptions of dairy farmers about aflatoxins and link it with aflatoxin mitigation programs on milk in Pakistan.

Post-cardiac surgery outcomes following COVID-19 infection in unvaccinated patients.

The provision of cardiac surgery services nationwide has been affected by the COVID-19 pandemic. We noticed a high COVID-19 mortality rate in unvaccinated patients who were diagnosed with COVID-19 after recent cardiac surgery. All the patients were tested negative for COVID-19 before surgery.

Natural and anthropogenic forces on suspended sediment dynamics in Asian estuaries.

Climate change and anthropogenic activities are affecting the hydrological conditions of rivers and may have altered nutrient and suspended sediments released into coastal seas. However, testing this hypothesis is difficult, confounded by the lack of observational data and the unavailability of globally accepted suspended sediment concentration (SSC) algorithms. Here, we analyzed the trends in SSC (2000-2020) at the mouths of 10 major Asian rivers using 10 available satellite-SSC algorithms.

Imminent threat of rock-ice avalanches in High Mountain Asia.

Upsurge of glacier-related hazards in High Mountain Asia (HMA) has been evident in recent years due to global warming. While many glacial-related hazards are instantaneous, some large landslides were preceded by slow gravitational deformation, which can be predicted to evade catastrophes. Here, we present robust evidence of historical deformation in 2021 Chamoli rock-ice avalanche of Himalaya using space imaging techniques.

Outcome of adult cardiac surgery following COVID-19 infection in unvaccinated population in a national tertiary centre.

Background: Ever since COVID-19 was declared a pandemic, the world medical landscape has changed dramatically. As cardiac surgeons we not only have the duty to protect our patients and staff from COVID-19 infection, but we are also tasked with the responsibility to ensure those cardiovascular patients awaiting surgery are not harmed from an extended delay in surgery as the world comes to a halt from COVID-19. Currently there is limited literature on the outcome of cardiac surgery in the pre-operative Covid positive group.

Incidence and Outcomes of Postoperative Atrial Fibrillation after Coronary Artery Bypass Grafting of a Randomized Controlled Trial: A Blinded End-of-cycle Analysis.

Objective: The objective of this study is to analyse the incidence of postoperative atrial fibrillation (POAF), demography, post-operative outcomes including morbidity and mortality, length of Cardiac Intensive Care Unit (CICU) stay, High Dependency Unit (HDU) stay, and total hospital stay in patients undergoing coronary bypass grafting (CABG) at Institut Jantung Negana (IJN).

Methods: We conducted a prospective, randomised, controlled trial. We supplied the treatment group with Tocovid capsules and the control group with placebo containing palm superolein.

Outcome of chest re-exploration for haemostasis in intensive care unit post-cardiac surgery: A retrospective analysis.

Introduction: Chest re-exploration is potentially life-saving in the treatment of early post-operative complications of open-heart surgery such as for surgical haemostasis, hemodynamic instability, and cardiac arrest. The procedure is often performed in the intensive care unit (ICU) rather than in the operating theatre (OT). The incidence of chest reexploration may range from 2 to 12%.