Publications by authors named "Yuntian Guo"
This experimental study was conducted to synthesize magnesium oxide (MgO) nanoparticles and investigate their efficiency in removing arsenic, brilliant cresyl blue, and neutral red from aqueous solutions. The MgO nanoparticles were characterized using X-ray diffraction (XRD), energy dispersive X-ray (EDS), Fourier-transform infrared spectroscopy (FTIR), and field emission scanning electron microscopy (FESEM) analyses. The results revealed that the synthesized MgO nanoparticles had a spherical structure with an estimated average size of approximately 30 nm.
View Article and Find Full Text PDFThe packaging problem with petroleum-based synthetic polymers prompts the development of edible packaging films. The high value-added reuse of navel orange peel pomace, which is rich in bioactive compounds, merited more considerations. Herein, nanocellulose (ONCC) and soluble dietary fiber (OSDF) from navel orange peel pomace are firstly used to prepare dietary fiber-based edible packaging films using a simple physical blend method, and the impact of ONCC on the film's properties is analyzed.
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- Antiretroviral therapy (ART) effectively lowers viral loads in HIV-infected individuals, but some still experience poor immune recovery; researchers studied the immune cell profiles to understand this phenomenon better.
- The study analyzed immune cells from different groups (treatment-naïve, immunological non-responders, immunological responders, and healthy controls) using mass cytometry and identified correlations between immune cell types and various health indicators like viral RNA and CD4 counts.
- Key findings included observed immune cell activation, exhaustion, and changes in specific immune cell subsets among treatment-naïve individuals, indicating a relationship between immune cell composition and the success of ART, which may help tackle incomplete immune recovery in certain patients.
Article Synopsis
- The intestinal epithelial barrier is crucial in the progression of HIV disease, but its damage in different patient groups is not well understood.
- A study compared intestinal damage and related markers among immunological responders (IRs), immunological non-responders (INRs), and healthy controls.
- It found that both IRs and INRs had persistent intestinal damage, with INRs showing more severe damage, which was linked to higher HIV DNA levels and lower CD4 T cell counts.
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- Blood microbiota in HIV-infected individuals is not well understood, even though their gut microbiota shows changes.
- Evidence suggests that HIV-infected individuals have greater diversity in their blood microbiota, possibly due to gut microbes moving into the bloodstream.
- Certain microbes have been identified that are associated with inadequate immune recovery, laying the groundwork for potential therapies aimed at improving immune function in HIV patients.
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- Studies on gut immune balance in HIV patients are limited; this research focuses on intestinal samples from different groups: immunological nonresponders (INRs), immunological responders (IRs), and HIV-negative controls.
- Key findings reveal that INRs have reduced Th17 and increased Treg cell counts compared to IRs, highlighting a significant difference in the Th17/Treg ratio, which is linked to markers of intestinal health like ZO-1 and I-FABP.
- The Th17/Treg ratio correlates positively with CD4 T cell counts and negatively with intestinal HIV DNA, suggesting that an imbalance in these cells indicates incomplete immune recovery and is associated with intestinal damage in HIV-infected individuals.
Article Synopsis
- The study aimed to investigate how serum globulin levels relate to immune restoration and the size of the HIV reservoir in patients on long-term antiretroviral therapy (ART).
- Researchers monitored 13 HIV patients on ART for 5 years, measuring various markers including serum globulin, HIV DNA, and T-cell activation indicators at multiple time points.
- Results indicated that higher serum globulin levels were linked to larger HIV reservoirs and more activated T-cells, suggesting a potential role of serum globulin in immune response and control of HIV during extended ART.
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- The study aimed to analyze β7 CD4 T cells in HIV-1 infected patients to understand their role in disease progression.
- The research included 124 HIV-1 patients and healthy controls, assessing β7 CD4 T cell characteristics using flow cytometry and other techniques.
- Results showed a decrease in β7 CD4 T cell frequency correlated with worsening disease, with these cells being more susceptible to HIV-1 infection and associated with a Th17 phenotype.