Publications by authors named "Yunqing Zeng"

Introduction: Endoscopic antireflux therapy has shown promising potential in the treatment for gastro-oesophageal reflux disease (GERD). However, there is currently no universally accepted standard for endoscopic surgery. Therefore, we introduced antireflux mucosal valvuloplasty (ARMV), an innovative endoscopic treatment for GERD.

View Article and Find Full Text PDF

Background: The necessity of computed tomography (CT) scan for detecting potential lymph node metastasis (LNM) in early esophageal squamous cell carcinoma (ESCC) before endoscopic and surgical treatments is under debate.

Methods: Patients with histologically proven ESCC limited to the mucosa or submucosa were examined retrospectively. Diagnostic performance of CT for detecting LNM was analyzed by comparing original CT reports with pathology reports.

View Article and Find Full Text PDF
Article Synopsis
  • The study focused on the impact of lymph node ratio on the prognosis of patients with duodenal adenocarcinoma and aimed to create a nomogram model to improve treatment decisions.
  • Data from 943 patients were analyzed to determine how various factors, including lymph node ratio, affected survival rates, with specific thresholds indicating poorer outcomes.
  • The findings support using a lymph node ratio-based nomogram for personalized treatment strategies, suggesting that high-risk patients may benefit from adjuvant chemotherapy, while low-risk patients might avoid unnecessary treatment.
View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on creating a predictive model for submucosal fibrosis in patients with early gastric cancer (EGC) who are undergoing endoscopic submucosal dissection (ESD).
  • Researchers analyzed data from patients treated at Qilu Hospital, using logistic regression to identify risk factors and develop a nomogram.
  • Results showed the model effectively predicted fibrosis risk with high accuracy, proving useful for endoscopists in clinical settings.
View Article and Find Full Text PDF

Background: The prognosis comparison between endoscopic therapy + partial splenic embolization (PSE) and Hassab's operation is unclear in the treatment of esophageal variceal bleeding in patients with liver cirrhosis. This study aimed to compare the outcome of endoscopic therapy + PSE (EP) with a combination of splenectomy + pericardial devascularization procedure, known as Hassab's operation (SH) for esophageal variceal bleeding in patients with liver cirrhosis with hypersplenism.

Methods: We enrolled 328 patients, including 125 and 203 patients who underwent EP and SH, respectively.

View Article and Find Full Text PDF

Background: Sarcopenia is a common complication of liver cirrhosis and can be used for predicting dismal prognostic outcomes. This study aimed to evaluate the role of sarcopenia in rebleeding and mortality of liver cirrhosis patients after endoscopic therapy.

Methods: The liver cirrhosis patients who received endoscopic treatment were enrolled.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the relationship between adipose tissue measured by CT scans and the outcomes of variceal bleeding in cirrhotic patients undergoing endoscopic therapy.
  • Results indicate that only the subcutaneous adipose tissue index (SATI) is significantly associated with higher risks of rebleeding and mortality, with low SATI levels linked to worse outcomes.
  • It suggests that assessing SATI can help identify patients who may benefit from targeted nutritional interventions and improve risk classification.
View Article and Find Full Text PDF

Background: This study aimed to compare the efficacy of partial splenic embolization (PSE) combined with endoscopic therapy and endoscopic therapy alone in cirrhosis patients with acute variceal bleeding (AVB) and hypersplenism.

Methods: Cirrhosis patients with AVB who visited three hospitals from June 2016 to June 2022 were prospectively enrolled and randomly allocated to either the endoscopic therapy combined with PSE group (EP group) or the endoscopic intervention group (E group) in a 1:1 ratio. The primary endpoint of the study was re-bleeding of varices during follow-up, and the secondary endpoints were the recurrence of varices, death, and adverse events.

View Article and Find Full Text PDF

Background: The severity of metabolic dysfunction-associated fatty liver disease (MAFLD) reportedly plays a part in the etiology of colorectal tumors. However, there is no consensus.

Methods: Studies relevant with the impact of MAFLD severity on the risk of colorectal neoplasms published before 24th April 2022 were screened.

View Article and Find Full Text PDF
Article Synopsis
  • Gastric cancer (GC) is a prevalent type of cancer known for its poor outcomes, and its development is significantly influenced by epigenetic changes, particularly DNA methylation.
  • The article discusses research on how DNA methylation is linked to the causes, diagnosis, treatment, and prognosis of gastric cancer.
  • The goal is to identify cancer biomarkers that could help address critical health issues related to gastric cancer.
View Article and Find Full Text PDF

Objective: To investigate the current status of antibiotic use for very and extremely low birth weight (VLBW/ELBW) infants in neonatal intensive care units (NICUs) of Hunan Province.

Methods: The use of antibiotics was investigated in multiple level 3 NICUs of Hunan Province for VLBW and ELBW infants born between January, 2017 and December, 2017.

Results: The clinical data of 1 442 VLBW/ELBW infants were collected from 24 NICUs in 2017.

View Article and Find Full Text PDF