Publications by authors named "Yunping Xue"
Article Synopsis
- Polycystic ovarian syndrome (PCOS) involves hormonal imbalances, leading to issues like infertility, and the study focused on how the hormone dihydrotestosterone affects a specific microRNA (miR-379-5p) released from granulosa cells in developing ovarian follicles.
- Compared to non-PCOS individuals, those with PCOS show elevated testosterone, reduced exosomal miR-379-5p levels, and decreased granulosa cell growth, hinting at a link between androgens and miR-379-5p levels.
- The research found that androgens promote miR-379-5p release in early follicle stages but not later ones, suggesting that improper regulation of this process
Peptidomic Analysis of Endometrial Tissue from Patients with Ovarian Endometriosis.
Cell Physiol Biochem
August 2018
Background/aims: Ovarian endometriosis (OvE) is ovarian cyst that is lined with endometrial tissue. They are found in 17-44% of women with endometriosis. Their clinical manifestations include pelvic pain, dysmenorrhea, dyspareunia, and infertility.
View Article and Find Full Text PDFPolycystic ovarian syndrome (PCOS) is a common endocrinopathy associated with increased risk of metabolic disorders. Prevalence of adiposity and obesity is greater in women suffering from PCOS. Moreover, adipose tissue dysfunction has been demonstrated in PCOS patients, particularly in abdominal adipose tissue.
View Article and Find Full Text PDFPolycystic ovary syndrome (PCOS) is a common reproductive endocrine disease, which is characterized by hyperandrogenism (HA), chronic anovulation, polycystic ovaries, insulin resistance, and obesity. At present, the mechanism by which PCOS/HA occurs has not been fully elucidated, thus, the mechanisms behind and interventions for HA in PCOS are current hot topics in research. MiRNAs have recently been shown to serve as diagnostic or prognostic biomarkers in patients with cancer.
View Article and Find Full Text PDFComparison of three treatment strategies for cesarean scar pregnancy.
Arch Gynecol Obstet
August 2017
Purpose: To explore the optimal treatment for cesarean scar pregnancy.
Method: In total, 86 women diagnosed with a cesarean scar pregnancy were divided into three groups according to treatment. The human chorionic gonadotrophin (hCG) decline percentage, intraoperative blood loss and success rate were analyzed in Group A [combination of uterine arterial embolization (UAE), local methotrexate (MTX) injection and dilation & curettage (D&C)], Group B (combination of UAE and local MTX injection) and Group C (D&C).
Effect of vitamin D on biochemical parameters in polycystic ovary syndrome women: a meta-analysis.
Arch Gynecol Obstet
February 2017
Aim: To investigate the therapeutical effect of vitamin D supplementation on the metabolism and endocrine parameters of PCOS patients.
Materials And Methods: Clinical studies investigating the therapeutic effect of vitamin D supplementation on PCOS patients were selected by searching PubMed, Embase, The Cochrane library and Web of Science until April 2016. The included articles were selected according to the inclusion criteria.