Design of a graphene-based chiral trifunctional tunable terahertz metasurface.

Driven by the pressing demand for integration and miniaturization within the terahertz (THz) spectrum, this research introduces an innovative approach to construct chiral structures using dichroism as the target function. This initiative aims to tackle the prevalent issues of single-functionality, narrow application scope, and intricate design in conventional metasurfaces. The proposed multifunctional tunable metasurface employs a graphene-metal hybrid structure to address the critical constraints found in existing designs.

The trogocytosis of neutrophils on initial transplanted tumor in mice.

The role of neutrophils in tumor initiation stage is rarely reported because of the lack of suitable models. We found that neutrophils recruited in early tumor nodules induced by subcutaneous inoculation of B16 melanoma cells were able to attack tumor cells by trogocytosis. The anti-tumor immunotherapy like peritoneal injection with TLR9 agonist CpG oligodeoxynucleotide combined with transforming growth factor β2 inhibitor TIO3 could increase the trogocytic neutrophils in the nodules, as well as CD8 T cells, natural killer (NK) cells, and their interferon-γ production.

A Deep Learning-Enabled Skin-Inspired Pressure Sensor for Complicated Recognition Tasks with Ultralong Life.

Flexible full-textile pressure sensor is able to integrate with clothing directly, which has drawn extensive attention from scholars recently. But the realization of flexible full-textile pressure sensor with high sensitivity, wide detection range, and long working life remains challenge. Complex recognition tasks necessitate intricate sensor arrays that require extensive data processing and are susceptible to damage.

Lead-Free Double Perovskite Semiconductor with Rigid Spacer-Induced High-T Dielectric Switch Features.

Layered hybrid perovskites possess exceptional semiconductor features and structural versality, making them viable candidates for developing multifunctional dielectric phase-transition materials (PTMS). However, most PTMs based on layered hybrid perovskites still suffer from Pb toxicity and low operating temperature. The recently developed hybrid double perovskites provide a new routine to designed PTMs with desired working performance and environment-friendly chemical compositions.

Incorporation of a TGF-β2-inhibiting oligodeoxynucleotide molecular adjuvant into a tumor cell lysate vaccine to enhance antiglioma immunity in mice.

Introduction: Transforming growth factor β2 (TGF-β2), also known as glioma-derived T-cell suppressor factor, is associated with the impairment of tumor immune surveillance. Therefore, blocking TGF-β2 signaling probably be a feasible strategy to develop a novel type of adjuvant for glioma vaccines to enhance antitumor immunity.

Methods: A TGF-β2 inhibitory oligodeoxynucleotide, TIO3, was designed with sequences complementary to the 3' untranslated region of TGF-β2 mRNA.

Toward Efficient Two-Photon Circularly Polarized Light Detection through Cooperative Strategies in Chiral Quasi-2D Perovskites.

Organic-inorganic hybrid perovskites carry unique semiconducting properties and advanced flexible crystal structures. These characteristics of organic-inorganic hybrid perovskites create a promising candidacy for circularly polarized light (CPL) detection. However, CPL detections based on chiral perovskites are limited to UV and visible wavelengths.

Immunotherapy for lung cancer combining the oligodeoxynucleotides of TLR9 agonist and TGF-β2 inhibitor.

Tumor immunotherapies have shown promising antitumor effects, especially immune checkpoint inhibitors (ICIs). However, only 12.46% of the patients benefit from the ICIs, the rest of them shows limited effects on ICIs or even accelerates the tumor progression due to the lack of the immune cell infiltration and activation in the tumor microenvironment (TME).

Chain-to-Layer Dimensionality Engineering of Chiral Hybrid Perovskites to Realize Passive Highly Circular-Polarization-Sensitive Photodetection.

Chiral hybrid perovskites (CHPs), aggregating chirality and favorable semiconducting properties in one, have taken a prominent position in direct circularly polarized light detection (CPL). However, passive high circular polarization sensitivity () photodetection in CHPs is still elusive and challenging. Benefitting from efficient control and turning of carrier transport of CHPs by dimensional engineering, here, we unprecedentedly proposed a chain-to-layer dimensionality engineering to realize high- passive photodetection.

Robust Spin-Dependent Anisotropy of Circularly Polarized Light Detection from Achiral Layered Hybrid Perovskite Ferroelectric Crystals.

Circularly polarized light (CPL) detection has sparked overwhelming research interest for its widespread chiroptoelectronic and spintronic applications. Ferroelectric materials, especially emerging layered hybrid perovskite ferroelectrics, exhibiting striking bulk photovoltaic effect (BPVE) present significant possibilities for CPL detection by a distinctive working concept. Herein, for the first time, we demonstrate the realization of robust angular anisotropy of CPL detection in a new layered hybrid perovskite ferroelectric crystal (CPA)FAPbBr (, CPA is chloropropylammonium, FA is formamidinium), which crystallized in an optically active achiral polar point group.

Self-Assembly of 2D Hybrid Double Perovskites on 3D Cs AgBiBr Crystals towards Ultrasensitive Detection of Weak Polarized Light.

We report the self-assembly of 2D double perovskite (BLA) CsAgBiBr (BLA=benzylammonium) on 3D Cs AgBiBr crystals, providing the first demonstration of polarization-sensitive photodetection using lead-free double perovskite heterocrystals (HCs). The (BLA) CsAgBiBr /Cs AgBiBr HC successfully combines the anisotropy of 2D double perovskites with the well-defined interface provided by heterogeneous integration. Driven by the built-in electric field in junction, photodetectors of HCs exhibit unique polarization dependence of zero-bias photocurrent with a large anisotropy ratio up to 9, which is 6 times amplified as compared to the pristine 2D (BLA) CsAgBiBr .

Realization of In-Plane Polarized Light Detection Based on Bulk Photovoltaic Effect in A Polar Van Der Waals Crystal.

2D van der Waals materials are widely explored for in-plane polarized light detection owing to their distinctive in-plane anisotropic feature. However, most of these polarized light-sensitive devices root in their low symmetry of in-plane structure and work depending on external power sources, which greatly impedes the simplification of integrated devices and sustainable development. Bulk photovoltaic effect (BPVE), which separates photoexcited carriers via built-in electric field without an external power source and shows an angle-dependence on light polarization, is promising for self-powered polarized light detection to break through the restriction of in-plane anisotropy.

Epitaxial Growth of Centimeter-Sized Lead-Free (BA)CsAgBiBr/CsAgBiBr Heterocrystals for Self-Driven X-ray Detection.

Halide perovskite heterocrystals, composed of distinct perovskite single crystals, have generated great interest for both fundamental research and applied device designs. One of the key advantages of using such a heterocrystal is its built-in electric potential, which enhances charge transport and suppresses the noise in the solid-state devices. On the basis of this strategy, high-performance optoelectronic devices (e.

High-Curie Temperature Multilayered Hybrid Double Perovskite Photoferroelectrics Induced by Aromatic Cation Alloying.

Due to the breakthrough development of layered hybrid perovskites, the multilayered hybrid double perovskites have emerged as outstanding semiconducting materials owing to their environmental friendliness and superior stability. Despite recent booming advances, the realization of above-room temperature ferroelectricity in this fascinating family remains a huge challenge. Herein, when the molecular design strategy of aromatic cation alloying is applied, an above-room temperature "green" bilayered hybrid double perovskite photoferroelectric, (CHCHNH)CsAgBiBr (), is successfully developed with a notable saturation polarization of 10.

Heterogeneous Integration of Chiral Lead-Chloride Perovskite Crystals with Si Wafer for Boosted Circularly Polarized Light Detection in Solar-Blind Ultraviolet Region.

Chiral hybrid organic-inorganic perovskites (HOIPs) have been well developed for circularly polarized light (CPL) detection, while new members that target at solar-blind ultraviolet (UV) region remain completely unexplored. Here, an effective design strategy to demonstrate circular polarization-sensitive solar-blind UV photodetection by growing wide-bandgap chiral HOIP [(R)-MPA] PbCl ((R)-MPA = methylphenethylammonium) single crystals onto silicon wafers, with well-defined heterostructures, is reported. The solid mechanical and electrical connection between the chiral HOIP and silicon wafer results in strong built-in electric field at heterojunction, providing a desirable driving force for separating/transporting carriers generated under CPL excitation at 266 nm.

Realization of vis-NIR Dual-Modal Circularly Polarized Light Detection in Chiral Perovskite Bulk Crystals.

Circularly polarized light (CPL)-sensitive direct detection is attracting increasing attention owing to its various optical technology applications and ultracompact device structures. However, current CPL-sensitive direct detection mainly focuses on a single mode, whereas the visible-near-infrared (vis-NIR) dual-modal detection, which is important for improving device sensitivity and night-vision performance, still remains to be explored. Here, for the first time, the vis-NIR dual-modal CPL-sensitive direct detection is presented in bulk single crystals of two-dimensional chiral perovskite (-BPEA)PbI (-BPEA = ()-1-(4-bromophenyl)ethylammonium).

Great Amplification of Circular Polarization Sensitivity via Heterostructure Engineering of a Chiral Two-Dimensional Hybrid Perovskite Crystal with a Three-Dimensional MAPbI Crystal.

Chiral hybrid perovskites have brought an unprecedented opportunity for circularly polarized light (CPL) detection. However, the circular polarization sensitivity of such a detector remains extremely low because of the high exciton recombination rate in those single-phase hybrid perovskites. Here, a heterostructure construction strategy is proposed to reduce the electron-hole recombination rate in a chiral hybrid perovskite and achieve CPL detectors with greatly amplified circular polarization sensitivity.

Bromine-Substitution-Induced High- Two-Dimensional Bilayered Perovskite Photoferroelectric.

High-Curie-temperature () ferroelectrics have exhibited broad applications in optoelectronic devices. Recently, two-dimensional multilayered perovskite ferroelectrics with excellent photoelectric attributes are attracting increasing interest as new systems of photoferroelectrics. However, the effective tuning of the value of a multilayered perovskite photoferroelectric system still remains a huge challenge.

Exploring a Fatigue-Free Layered Hybrid Perovskite Ferroelectric for Photovoltaic Non-Volatile Memories.

Through a functional unit-transmutation strategy, a fatigue-free layered hybrid perovskite ferroelectric (C H CH NH ) CsPb Br (BCPB) has been developed, which demonstrates stable spontaneous polarization (P ) of 6.5 μC cm and high Curie temperature up to 425 K. Meanwhile, BCPB shows splendid bulk photovoltaic effect (BPVE) properties with noticeable zero-bias photocurrent density (5 μA cm ), and high on/off switching ratio of current (over 3×10 ); these merits even overmatch the most known ferroelectric semiconductor BiFeO .

[(N-AEPz)ZnCl]Cl: A "Green" Metal Halide Showing Highly Efficient Bluish-White-Light Emission.

Benefiting from their structural flexibility and solution processability, organic-inorganic metal halide hybrids with efficient white-light emission present a great promise for solid-state lighting and display applications. However, most of these reported high-performance single-component white-light materials contain lead. Herein, we report a "green" organic zinc halide, [(N-AEPz)ZnCl]Cl (; N-AEPz = -aminoethylpiperazine), exhibiting prominent bluish-white-light emission with a photoluminescence quantum efficiency as high as 11.

(CHNI)AgBiI: a direct-bandgap layered double perovskite based on a short-chain spacer cation for light absorption.

A new iodide layered double perovskite (CHNI)AgBiI (IPAB) has been developed based on a short-chain spacer cation, which is the first homologous compound in iodide double perovskites that adopt the Ruddlesden-Popper structure type. Importantly, IPAB is a promising environmentally friendly alternative to the recently rapidly progressing lead halide semiconductors owing to its narrow direct-bandgap of 1.87 eV and excellent stability.

Exploiting the Bulk Photovoltaic Effect in a 2D Trilayered Hybrid Ferroelectric for Highly Sensitive Polarized Light Detection.

Polarized light detection is attracting increasing attention for its wide applications ranging from optical switches to high-resolution photodetectors. Two-dimensional (2D) hybrid perovskite-type ferroelectrics combining inherent light polarization dependence of bulk photovoltaic effect (BPVE) with excellent semiconducting performance present significant possibilities. Now, the BPVE-driven highly sensitive polarized light detection in a 2D trilayered hybrid perovskite ferroelectric, (allyammonium) (ethylammonium) Pb Br (1), is presented.

Highly Oriented Thin Films of 2D Ruddlesden-Popper Hybrid Perovskite toward Superfast Response Photodetectors.

2D hybrid perovskites have shown great promise in the photodetection field, due to their intriguing attributes stemming from unique structural architectures. However, the great majority of detectors based on this 2D system possess a relatively low response speed (≈ms), making it extremely urgent to develop new candidates for superfast photodetection. Here, a new organic-inorganic hybrid perovskite, (PA) (FA)Pb I (EFA, where PA is n-pentylaminium and FA is formamidine), which features the 2D Ruddlesden-Popper type perovskite framework that is composed of the corner-sharing PbI octahedra is reported.

Tailored Synthesis of an Unprecedented Pb-Mn Heterometallic Halide Hybrid with Enhanced Emission.

Organic-inorganic lead halide hybrids have attracted extensive interest in solid-state lighting, due to their superior color tunability and low-cost solution processing. However, the relatively low photoluminescence quantum efficiency (PLQE) is a common issue for most bulk lead halide hybrids. Inspired by the intriguing luminescence properties of heterometallic complexes, we rationally developed an unprecedented two-dimensional (2D) Pb-Mn heterometallic halide hybrid, (CHN)PbMnCl (), through a precisely tailored synthetic approach based on (CHN)PbCl ().

Exploration of Chiral Organic-Inorganic Hybrid Semiconducting Lead Halides.

Organic-inorganic lead halides have recently emerged as promising alternatives to conventional optoelectronic materials, considering their intriguing physical properties. However, organic-inorganic lead halides featuring chirality are seldom explored. Here, a pair of enantiomorphic organic-inorganic hybrid semiconducting lead halides, (R-C H N )PbBr (1R) and (S-C H N )PbBr (2S), were successfully obtained with the templating of chiral amines.