Publications by authors named "Yunmi Qiu"

Rosacea is a chronic, inflammatory dermatological condition primarily affecting the central face, including the cheeks, nose, chin, and forehead [1]. It presents with erythema, phymatous changes, papules, pustules, and telangiectasia. The pathogenesis of rosacea is still unknown.

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Dupilumab was the first biological medication licensed to treat atopic dermatitis (AD), and it has shown remarkable effectiveness and safety in the treatment of moderate-to-severe atopic dermatitis. There are limited drug-related adverse events associated with dupilumab in atopic dermatitis (AD) treatment. Here, we present two cases of local infection during the treatment of atopic dermatitis with dupilumab.

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Background/objectives: The lip is a unique tissue type that acts as a "barrier" to the mouth and receives many external stimuli. It is also a common symptom in atopic dermatitis. Dupilumab was the first targeted biological drug approved for the treatment of moderate-to-severe atopic dermatitis (AD).

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Article Synopsis
  • Atopic dermatitis (AD) is a chronic skin condition, and dupilumab is the first biological treatment for this disease, though it can lead to a condition called psoriasiform erythema (PE) in some patients, including children.
  • This study examined two 17-year-old twin patients with AD who developed PE after starting dupilumab, focusing on cytokine gene expression during this transition.
  • Results indicated that the twins experienced significant changes in their skin, with specific histopathological features and elevated levels of certain cytokines like IL-17A, leading to a treatment switch from dupilumab to Baricitinib, which improved their skin condition.
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Chronic actinic dermatitis (CAD) is a rare chronic immunological photo-dermatosis resulting in pruritic eczematous eruption on sun-exposed skin to ultraviolet (UV) light. The disease mechanism may include a delay-type hypersensitivity reaction to an endogenous photo-induced antigen, postulated to be UVR-altered DNA, but the exact pathophysiology is unknown. Minimum erythema dosing and patch testing are diagnostic tools of CAD.

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