Publications by authors named "Yunlong Dai"

Hepatic hemangioma, focal nodular hyperplasia, and hepatic adenoma are the most common benign solid liver tumors. However, their surgical indications have been the subject of debate. Minimally invasive liver resection reduces the cost of surgery and may lead to overtreatment of benign liver tumors.

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Background: Our study aims to investigate the effects of the knockout of long non-coding RNA LSINCT5 (lncRNA LSINCT5) on the proliferation, apoptosis, epithelial-mesenchymal transition (EMT), and p38MAPK pathway of pancreatic cancer PANC-1 cells, to provide a basis for searching for the therapeutic targets of pancreatic cancer.

Methods: The laboratory findings and clinical data of 21 patients with pancreatic cancer were retrospectively collected, and the survival rates of patients with high or low lncRNA LSINCT5 expressions were analyzed. PANC-1 cells were randomly divided into the control group, shRNA-NC group, and sh-LSINCT5 group, and the constructed sh-LSINCT5 and shRNA-NC vectors were transfected into the corresponding cells.

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A new strategy for sensitive detection using a dual-template molecularly imprinted based electrochemical sensor was developed using thionine as an electrochemical probe. A single-signal for the non-electroactive template and a dual-signal for the electroactive template in the selective and sensitive detection have been achieved on the prepared sensor.

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A new strategy based on sign-on and sign-off was proposed for propyl gallate (PG) determination by an electrochemical sensor. The successively modified poly(thionine) (PTH) and molecular imprinted polymer (MIP) showed an obvious electrocatalysis and a good recognition toward PG, respectively. Furthermore, the rebound PG molecules in imprinted cavities not only were oxidized but also blocked the electron transmission channels for PTH redox.

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A facile electrochemical sensor for hydroquinone (HQ) and catechol (CC) determination was successfully fabricated by the modification of poly(3-aminophenylboronic acid) (pAPBA) film and multi-walled carbon nanotubes (MWCNTs) on a glassy carbon electrode (pAPBA/MWCNTs/GCE). The prepared sensor was characterized by scanning electron microscope and electrochemical impedance spectroscopy. Under optimal conditions, differential pulse voltammetry was employed to quantify individual HQ and CC within the concentration range of 5.

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A new strategy for a composite film based electrochemical sensor was developed in this work. A layer of conductive film of poly(p-aminobenzene sulfonic acid) (pABSA) was electropolymerized onto glassy carbon electrode surface and exhibited a high electrocatalytic active for paracetamol (PR) redox. The subsequent formation of a layer of molecular imprinted polymer (MIP) film on pABSA modified electrode endowed the sensor with plentiful imprinted cavities for PR specific adsorption.

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