Publications by authors named "Yunjian Fu"
Clostridium perfringens (C. perfringens) causes avian necrotic enteritis, leading to huge economic losses to the poultry industry. This pathogen induces host immunosuppression; however, the molecular mechanism is still unclear.
View Article and Find Full Text PDFInfection of piglets with Glaesserella parasuis (G. parasuis) induces host immunosuppression. However, the mechanism underlying the immunosuppression of piglets remains unclear.
View Article and Find Full Text PDFGlaesserella parasuis (G. parasuis) induces vascular damage and systemic inflammation. However, the mechanism by which it causes vascular damage is currently unclear.
View Article and Find Full Text PDFArticle Synopsis
- Poultry necrotic enteritis is a serious disease in chickens that can be controlled with antibiotics, but rising antibiotic resistance is a concern.
- Anemoside B4 has anti-inflammatory and immunomodulatory properties and was tested for its effects on this disease, showing it inhibited harmful processes in Caco-2 cells without exhibiting antibacterial activity.
- The study found that Anemoside B4 improved health markers in infected chickens, reduced tissue damage, and enhanced protective proteins in the intestines, demonstrating its potential as an alternative treatment.
Article Synopsis
- - Glaesserella parasuis is a bacterial pathogen that causes Glässer's disease in piglets, leading to potential immunosuppression, prompting researchers to study its effects on the immune response.
- - In a controlled experiment, 20 piglets were divided into infection and control groups to analyze changes in spleen immune cell differentiation and PD-1/PD-L1 expression after being infected with the bacteria.
- - The study discovered significant differences in protein expression in the spleen tissue of infected piglets, with 596 proteins showing changes linked to immune responses, marking the first investigation of PD-1/PD-L1 in the context of immunosuppression in piglets.