Toxicity of a novel antifungal agent (ATB1651 gel) in Yucatan minipigs following 4 weeks of daily dermal administration.

ATB1651 gel is an antifungal drug candidate that enhances antifungal activity through substitution of several aryl rings, alkyl chains, and methyl groups. To ensure safety of use of ATB1651 gel, assessment of its potentially toxic side effects is necessary. In this study, we examined the repeated-dose toxicity of ATB1651 gel to Yucatan minipigs in accordance with the Good Laboratory Practice guidelines.

Traumatic Stress of Frontline Workers in Culling Livestock Animals in South Korea.

The last decade brought several devastating outbreaks of foot and mouth disease and avian influenza in South Korea, which had been handled through preventive culling, despite the controversy surrounding its efficiency and ethical considerations. Notably, the lack of regulations on culling processes has exposed the workers to extremely harsh working conditions. This study investigates the effect of culling jobs on the mental health of the frontline workers, based on 200 samples collected through a web-based survey conducted on participants with experience of culling tasks.