The Causal Relationships Between Extrinsic Exposures and Risk of Prostate Cancer: A Phenome-Wide Mendelian Randomization Study.

Background: Prostate cancer is the second most common cancer in males worldwide, and multitudes of factors have been reported to be associated with prostate cancer risk.

Objectives: We aim to conduct the phenome-wide exposed-omics analysis of the risk factors for prostate cancer and verify the causal associations between them.

Methods: We comprehensively searched published systematic reviews and meta-analyses of cohort studies and conducted another systematic review and meta-analysis of the Mendelian randomization studies investigating the associations between extrinsic exposures and prostate cancer, thus to find all of the potential risk factors for prostate cancer.

Risk factors for the recurrence of early hepatocellular carcinoma treated by percutaneous radiofrequency ablation with a multiple-electrode switching system: a multicenter prospective study.

Purpose: To investigate the long-term efficacy of radiofrequency ablation (RFA) with a multiple-electrode switching system (MESS) in the treatment of early hepatocellular carcinoma (HCC) and evaluate the patterns and risk factors of intrahepatic recurrence of HCC after RFA.

Methods: In total, 139 patients with early HCC who underwent RFA with MESS as primary treatment at multiple centers were prospectively enrolled according to the inclusion criteria. We evaluated the local tumor progression (LTP), intrahepatic distant recurrence (IDR), the incidence of cumulative disease-free survival (DFS), LTP-free survival, IDR-free survival, and overall survival.

Design of Double-Layer Electrically Extremely Small-Size Displacement Sensor.

In this paper, a displacement sensor with an electrically extremely small size and high sensitivity is proposed based on an elaborately designed metamaterial element, i.e., coupled split-ring resonators (SRRs).

miR-103 promotes hepatocellular carcinoma cell proliferation and migration in the simulation transition zone of RFA through PI3K/Akt signaling pathway by targeting PTEN.

Radiofrequency ablation (RFA) is a potentially curative therapy for nontransplantable hepatocellular carcinoma (HCC). However, as tumor size increases, incomplete RFA can increase rates of local recurrence and tumor progression. As such, there remains a need to identify potential biologic mechanisms mediating HCC response to thermal ablation.

High-efficiency directional excitation of spoof surface plasmons by periodic scattering cylinders.

In this Letter, we propose and experimentally demonstrate a simple but efficient method to excite spoof surface plasmons (SSP) through periodic metallic cylinders at microwave frequencies. The rigorous multiple scattering theory indicates that most of the incident propagating waves can pass the cylinders and be converted into the desired harmonics. Furthermore, by tuning the incident angle, controlling the directions of the excited SSP at different frequencies is also realized.

Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma.

Purpose: Radiofrequency ablation (RFA) is widely accepted as a curative treatment for small hepatocellular carcinoma (HCC). However, insufficient RFA (IRFA) can lead to rapid local recurrence. The underlying mechanisms remain poorly understood.

Experimental demonstration of an ultra-broadband subwavelength resolution probe from microwave to terahertz regime.

An ultra-broadband subwavelength resolution probe that consists of a Teflon rod and six metallic strips is developed for the near-field imaging system. The slit between two metallic strips maintains quasi-TEM modes, avoiding the problem of low coupling efficiency caused by the cutoff effect. The numerical calculations visualize the process of energy compression into a 0.

Long noncoding RNA expression profiles in sub-lethal heat-treated hepatoma carcinoma cells.

Background: Sub-lethal heat treatment characterizes a transition zone of radiofrequency ablation (RFA) which explains hepatocellular carcinoma (HCC) residual cancer occurrence in this area after RFA treatment. The biochemistry of residual cancer cell recurrence is poorly understood, but long noncoding RNAs (lncRNAs) may have aberrant expression that is associated with diverse cancers. Thus, we measured lncRNA gene expression in sub-lethally heat-treated HCC cells using microarray.

Radiofrequency ablation using a multiple-electrode switching system for hepatocellular carcinoma within the Milan criteria: long-term results.

Purpose: To assess the long-term outcome of 516 consecutive patients treated with multiple-electrode switching system (MESS) radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) that met the Milan criteria.

Materials And Methods: We performed 522 MESS RFAs on 516 patients from December 2006 to June 2011. A total of 956 tumours that met the Milan criteria with an average diameter of 2.

Tunable Terahertz Deep Subwavelength Imaging Based on a Graphene Monolayer.

The resolution of conventional terahertz (THz) imaging techniques is limited to about half wavelength, which is not fine enough for applications of biomedical sensing and nondestructive testing. To improve the resolution, a new superlens, constructed by a monolayer graphene sheet combining with a grating voltage gate, are proposed in this paper to achieve deep super-resolution imaging in the THz frequency range. The main idea is based on the Fabry-Perot resonance of graphene edge plasmon waves.

Near-Field and Far-Field Directional Conversion of Spoof Surface Plasmon Polaritons.

A compact metallic meta-structure is proposed to realize directional conversion between spoof surface plasmon polaritons (SSPPs) and propagating waves at millimeter wave and THz frequencies. The structure is constructed by embedding two slits or multi-slits array into a subwavelength metallic reflection grating. When the back-side of the structure is illuminated by an oblique beam with a fixed incident angle, the propagating wave will be unidirectionally converted into SSPPs with a considerable efficiency.

Successful treatment of gastrointestinal stromal tumor with multiple liver metastases with radiofrequency ablation and imatinib: A case report.

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor of the gastrointestinal tract, and typically metastasize to the liver. In patients with recurrent metastatic GISTs, no single treatment is effective. The current study reports a case of GIST with 27 metastases in the liver, which was successfully treated using radiofrequency ablation (RFA) combined with surgical resection and imatinib therapy.

[Characteristics of volatile organic compounds during haze episode in Foshan city].

Volatile Organic Compounds (VOCs) in Foshan City were investigated in December 6 to 30 2008. The concentrations of VOCs in haze days were significantly higher than those in no-haze days. Toluene (68.