Introduction: While social networks have become an integral part of people's lives, they also bring the potential for negative consequences, with problematic social network use emerging as a noteworthy concern, especially among adolescents. Guided by social control theory, this study examined bidirectional relationships between problematic social network use and its influencing factors: school connectedness and social anxiety.
Methods: Random intercept cross-lagged panel models were employed to examine the bidirectional relationships among school connectedness, social anxiety, and problematic social network use.
is the most common fungal pathogen associated with human opportunistic infections. Invasive infections caused by are becoming increasingly serious. However, with the rising incidence of fungal infection, many fungi are resistant to commonly used drugs.
View Article and Find Full Text PDFResearch has demonstrated robust links between adolescent stress and serious psychological problems. The current study aimed to identify latent stress profiles of 1510 adolescents (59.7% females; M = 16.
View Article and Find Full Text PDFBioorg Med Chem Lett
September 2022
With the widespread use of azole antifungals in the clinic, the drug resistance has been emerging continuously. In this work, we have designed and prepared a series of novel indole and indoline derivatives, and in vitro antifungal activity against C. albicans were evaluated.
View Article and Find Full Text PDFWith the widespread use of azole antifungals in the clinic, the drug resistance has been emerging continuously. In this work, we focus on boron trifluoride etherate catalyzed condensation of indole and salicylaldehydes to form bis(indolyl)methanes (BIMs) in high yields, and in vitro antifungal activity against Candida albicans were evaluated. The results showed that most phenol-derived BIMs combined with fluconazole (FLC) exhibited good antifungal activity against sensitive and drug-resistant C.
View Article and Find Full Text PDFObjective: To investigate the occupational identity of primary health technicians in Qiqihar City and to analyze its influencing factors.
Methods: From September 2020 to October 2020, 436 primary health technicians were selected from the primary health centers in Qiqihar City using the convenience sampling method. After eight invalid questionnaires were excluded, the total number cases was 428.