Publications by authors named "Yunhe Lang"

In view of the significant role of reactive sulfur species (RSS) and reactive oxygen species (ROS) in maintaining the redox homeostasis of organisms, we proposed a colorimetric fluorescent probe (HTN) for reversible detection of HSO/HO and effective discrimination of HSO/ClO. C = C is the active site for the Michael addition of HSO and the oxidation of ClO. When HTN interacts with HSO and ClO, it exhibits fluorescence quenching.

View Article and Find Full Text PDF

Harmful cyanobacterial blooms and the released microcystins (MCs) caused serious environmental and public health concerns to drinking water safety. Photo-oxidation is an appealing treatment option and alternative to conventional flocculation and microbial antagonists, but the performances of current photosensitizers (either inorganic or organic) are unsatisfactory. Here, a polythiophene photosensitizer (PT10) with both high yield of reactive oxygen species (ROS) production (mainly O, Φ = 0.

View Article and Find Full Text PDF

Halo-fluoresceins are widely used in cell and tissue staining, intracellular sensing, and photodynamic therapy, but their notorious photo-instability and pH dependence restrict their applications, especially in long-term visible light exposure and acidic environments. To overcome these limitations, here a strategy is proposed of conjugating chitosan with the carboxyl group of halo-fluorescein (CS-halofluorescein). The cross-linked polymer chains and the hydrogen-bonding networks of chitosan help shielding out O from direct attacking the encapsulated halo-fluoresceins, leading to a two orders of magnitude lower photobleaching rate.

View Article and Find Full Text PDF

Microbial infections are currently one of the world's major public health concerns, the evolution of which has resulted in the development of multiple tolerances (not just drug or antibiotic resistance), including pH (from extremely acidic to alkaline). Currently various types of antimicrobials have been developed. Although effective, they seldom work in the full pH range due to the existence of acid-/base-reaction sites.

View Article and Find Full Text PDF

Ultraviolet radiation (UVR) is both useful to human beings and can cause irreversible harm of varying degrees (UVA, UVB, and UVC). Especially, in areas with excessive sunlight, the appearance of UVB results in an increased risk of skin cancer. On the other hand, UV lamps (254 nm, UVC) are widely used in disinfection (air, water, and factory food) and hospital sterilization; the leakage of UVC is thus sometimes inevitable, which may cause fatal injuries to the related staff.

View Article and Find Full Text PDF

DO plays important roles in a variety of fields (such as the nuclear industry and bioorganic analysis), and thus its isotopic purity (HO contents) is highly concerned. Due to its highly similar physical properties to HO and large excess amounts of HO over DO, it is challenging to distinguish DO from HO. On the basis of the characteristic NIR-II phosphorescence of singlet oxygen (O), and the fact that HO is a more efficient quencher for O than DO, here, we proposed to simply use the 1275 nm emission of O for the analysis of the isotopic purity of DO.

View Article and Find Full Text PDF

Horseradish peroxidase (HRP)-based assays feature particular interests because of the simple colorimetric readout. In these assays, 3,3',5,5'-tetramethylbenzidine (TMB) is the most widely used chromogenic substrates for HRP. The later research in nanozyme and DNAzyme also used TMB (the chosen substrate) because they are both HRP-mimics.

View Article and Find Full Text PDF

In this work, a new biological probe for human transferrin (hTf) detection based on a cyanine dye ETC supramolecular assembly was designed. In sub-micromolar level, apo-hTf could induced the ETC aggregations transferred from H-aggregations to J-band with color change from pink to blue, while holo-hTf hardly possessed the ability, indicating ETC could specifically identify apo-hTf. The present study allowed for apo-hTf detection in the range of 8-80 nM with a detection limit of 2.

View Article and Find Full Text PDF

As key molecules in most biological pathways, proteins physically contact one or more biomolecules in a highly specific manner. Several driving forces (i.e.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_session9hvfa5a20c68bsm07sqtqd502tiq66vm): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once