Extreme climate events, particularly droughts, pose significant threats to vegetation, severely impacting ecosystem functionality and resilience. However, the limited temporal resolution of current satellite data hinders accurate monitoring of vegetation's diurnal responses to these events. To address this challenge, we leveraged the advanced satellite ECOSTRESS, combining its high-resolution evapotranspiration (ET) data with a LightGBM model to generate the hourly continuous ECOSTRESS-based ET (HC-ET) for the middle and lower reaches of the Yangtze River Basin (YRB) from 2015 to 2022.
View Article and Find Full Text PDFIntroduction: Cerebral swelling and brain injury in ischemic stroke are closely related to increased vasopressin (VP) secretion. How to alleviate ischemic brain injury by suppressing VP hypersecretion through simply available approaches remains to be established.
Methods: Using a rat model of middle cerebral artery occlusion (MCAO), testing effects of the intranasal application of low concentration saline-0.
The development of cost-effective and highly efficient electrocatalysts is critical to help electrochemical non-enzymatic sensors achieve high performance. Here, a new class of catalyst, Ru single atoms confined on Cu nanotubes as a single-atom alloy (RuCu NTs), with a unique electronic structure and property, was developed to construct a novel electrochemical non-enzymatic glucose sensor for the first time. The RuCu NTs with a diameter of about 24.
View Article and Find Full Text PDFOvergrowth and intellectual disability disorders in humans are typified by length/height and/or head circumference ≥ 2 standard deviations above the mean as well as intellectual disability and behavioral comorbidities, including autism and anxiety. Tatton-Brown-Rahman Syndrome is one type of overgrowth and intellectual disability disorder caused by heterozygous missense mutations in the DNA methyltransferase 3A (DNMT3A) gene. Numerous DNMT3A mutations have been identified in Tatton-Brown-Rahman Syndrome patients and may be associated with varying phenotype severities of clinical presentation.
View Article and Find Full Text PDFCo-site interference is becoming prominent on some independent platforms (e.g., airplanes, satellites, space stations, and vessels).
View Article and Find Full Text PDFIt is critical to develop high-performance electrocatalyst for electrochemical nonenzymatic glucose sensing. In this work, a single-atom Pt supported on Cu@CuO core-shell nanowires (Pt /Cu@CuO NWs) for electrochemical nonenzymatic glucose sensor is designed. Pt /Cu@CuO NWs exhibit excellent electrocatalytic oxidation toward glucose with 70 mV lower onset potential (0.
View Article and Find Full Text PDFAstrocytic morphological plasticity and its modulation of adjacent neuronal activity are largely determined by astrocytic volume regulation, in which glial fibrillary acidic protein (GFAP), aquaporin 4 (AQP4), and potassium channels including inwardly rectifying K channel 4.1 (Kir4.1) are essential.
View Article and Find Full Text PDFIntroduction: In the regulation of oxytocin (OT) neuronal activity, hydrogen sulfide (H2S), a gaseous neurotransmitter, likely exerts an excitatory role. This role is associated with increased expression of astrocytic cystathionine-β-synthase (CBS), the key enzyme for H2S synthesis. However, it remains unclear whether H2S is mainly produced in astrocytes and contributes to the autoregulation of OT neurons.
View Article and Find Full Text PDFAim: Glial fibrillary acidic protein (GFAP) molecularly associates with aquaporin 4 (AQP4) in astrocytic plasticity. Here, we further examined how AQP4 modulates osmotic effects on vasopressin (VP) neurons in rat supraoptic nucleus (SON) through interactions with GFAP in astrocytes.
Methods: Brain slices from adult male rats were kept under osmotic stimulation.