Improvement of Temperature and Optical Power of an LED by Using Microfluidic Circulating System of Graphene Solution.

Electric devices have evolved to become smaller, more multifunctional, and increasingly integrated. When the total volume of a device is reduced, insufficient heat dissipation may result in device failure. A microfluidic channel with a graphene solution may replace solid conductors for simultaneously supplying energy and dissipating heat in a light emitting diode (LED).

Microfluidic chip of fast DNA hybridization using denaturing and motion of nucleic acids.

This study presents the effect of fluidic temperatures and velocities on improving DNA hybridization. The efficiency of hybridization could be improved by introducing elevated temperature in the hot region and velocity in the cold region. Compared with the conventional methods, this hybridization microchip was able to increase the hybridization signal 4.

Mixing enhancement of the passive microfluidic mixer with J-shaped baffles in the tee channel.

This study proposed a new design of a passive micromixer employing several J-shaped baffles in the tee channel to enhance mixing. The mixing performance of the device was investigated experimentally and by numerical simulation. The in-plane structured micromixer was fabricated using micromolding of SU-8 photoresist and PDMS.

Design of a recursively-structured valveless device for microfluidic manipulation.

A recursively-structured apparatus based on a pneumatic pumping structure has been investigated numerically and experimentally in the present study. For the T-connected channels, this apparatus demonstrated the ability to manipulate the liquid drop from a first channel to a second channel, while simultaneously preventing flow into the third channel. The microTAS research aimed at biochemical analysis miniaturization and integration has recently made explosive progress.

Microfluidic chip for high efficiency DNA extraction.

A high efficiency DNA extraction microchip was designed to extract DNA from lysed cells using immobilized beads and the solution flowing back and forth. This chip was able to increase the extraction efficiency by 2-fold when there was no serum. When serum existed in the solution, the extraction efficiency of immobilized beads was 88-fold higher than that of free beads.

Microfluidic chip for fast nucleic acid hybridization.

The design and experimental verification of a fast nucleic acid hybridization microchip using the fluidic velocity and strain rate effects was conducted. This hybridization chip was able to increase the hybridization signal 6-fold, reduce non-specific target-probe binding and background noise within 30 min, as compared to conventional hybridization methods, which may take from 4 h to overnight. Excellent correlation between experimental results and simulation analysis was obtained in this study.

Design of passive mixers utilizing microfluidic self-circulation in the mixing chamber.

This paper proposes the design of a passive micromixer that utilizes the self-circulation of the fluid in the mixing chamber for applications in the Micro Total Analysis Systems (microTAS). The micromixer with a total volume of about 20 microL and consisting of an inlet port, a circular mixing chamber and an outlet port was designed. The device was actuated by a pneumatic pump to induce self-circulation of the fluid.