Publications by authors named "Yung-Ann Chen"

Article Synopsis
  • - Longan, a fruit tree rich in phenolic components, may help reduce uric acid levels and protect against oxidative damage through anti-inflammatory mechanisms.
  • - A study tested longan extracts from flowers, seeds, and other parts on mice with induced hyperuricemia, revealing that flower extracts had the strongest xanthine oxidase (XO) inhibition and uric acid lowering effect.
  • - Two specific phytochemicals from longan flowers, proanthocyanidin A2 and acetonylgeraniin A, showed significant XO inhibitory activity in lab tests, suggesting their potential as new treatments for high uric acid levels.
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This paper reports a microfluidic device capable of generating oxygen gradients for cell culture using spatially confined chemical reactions with minimal chemical consumption. The microfluidic cell culture device is constructed by single-layer polydimethylsiloxane (PDMS) microfluidic channels, in which the cells can be easily observed by microscopes. The device can control the oxygen gradients without the utilization of bulky pressurized gas cylinders, direct addition of oxygen scavenging agents, or tedious gas interconnections and sophisticated flow control.

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