Unusual Temperature-Dependent Photoluminescence Due to Competing Excited-State Energy Transfer in Rare Earth Double Perovskites.

Lead-free halide double perovskites (DPs) have become a research hotspot in the field of photoelectrons due to their unique optical properties and flexible compositional tuning. However, the luminescence of DPs exhibits thermal quenching at high temperatures, which severely affects their further application. Herein, we synthesized the rare earth Dy and transition metal Mn codoped CsNaYCl rare earth DPs and characterized the optical properties using temperature-dependent photoluminescence spectra and time-resolved photoluminescence decay profiles at different temperatures.

Development and Application of Digital Human Models in the Field of Vehicle Collisions: A Review.

In the human-vehicle-road system of collisions, the human is the most important factor, and digital human models (DHMs) are developed with the aim of preventing or at least reducing human injury. Because most of the relevant literature is focused mainly on collisions in traffic accidents (TAs), only some of the literature reviewed in this paper involves research results on other aspects of collisions. In this review, based on the background of DHMs and the application of DHMs regarding human injury biomechanics in collisions field, research results regarding the development of DHMs are described, the methods for verifying such models are introduced, and the application of the research results is discussed based on the aspect of human injury biomechanics.

Apatinib suppresses breast cancer cells proliferation and invasion via angiomotin inhibition.

Breast cancer is a leading cause of cancer-related death in the women worldwide. Apatinib is a novel tyrosine kinase inhibitor that selectively binds and inhibits vascular endothelial growth factor receptor 2 (VEGFR-2). The clinical trials have demonstrated the objective efficacy of Apatinib against metastatic breast cancer.

X-linked inhibitor of apoptosis-associated factor l (XAFl) enhances the sensitivity of colorectal cancer cells to cisplatin.

The purpose of present study was to investigate the roles of X-linked inhibitor of apoptosis-associated factor l (XAFl) in regulation apoptosis of colorectal cancer (CRC) cells after treatment with cisplatin (DDP). A total of ten paired cancerous and non-cancerous tissues were collected from patients with CRC after surgery. The levels of XAFl protein were detected by Western blot.

Combination of gefitinib and DNA methylation inhibitor decitabine exerts synergistic anti-cancer activity in colon cancer cells.

Despite recent advances in the treatment of human colon cancer, the chemotherapy efficacy against colon cancer is still unsatisfactory. In the present study, effects of concomitant inhibition of the epidermal growth factor receptor (EGFR) and DNA methyltransferase were examined in human colon cancer cells. We demonstrated that decitabine (a DNA methyltransferase inhibitor) synergized with gefitinib (an EGFR inhibitor) to reduce cell viability and colony formation in SW1116 and LOVO cells.