Study on Fatigue Cracking of Diaphragm's Arc Opening of OSD in Steel Bridges by Using Biaxial Stress Method.

Changes in loading position have a significant impact on the stress field of each vulnerable area of an orthotropic steel deck (OSD). The arc opening area of the diaphragm and the connecting area between the U-rib and the diaphragm under the moving load are prone to fatigue cracking. By comparing the stress responses under different methods, the hot spot stress (HSS) method is used as the main stress extraction method in fatigue performance evaluation.

Isolation, X-ray crystal structure of the new diterpene and identification of others lignans and flavonoids from the fresh needles of .

Three new compounds, namely massonside C (), massonianoside F (, and 3, 8-dimethyl- herbacetin-7-O-β-D-glucopyranoside (), together with five known compounds (-), were isolated from the fresh needles of . Their structures were established by 1D, 2D NMR, HRMS and comparison with the literature data. The absolute configuration of was confirmed by a combination of X-ray single crystal analysis.

Isolariciresinol-9'-O-α-L-arabinofuranoside protects against hydrogen peroxide‑induced apoptosis of human umbilical vein endothelial cells via a PI3K/Akt/Bad‑dependent pathway.

Isolariciresinol-9'-O-α-L-arabinofuranoside (MWS‑19) isolated from Pinus massoniana Lamb. Fresh pine needles is the major ingredient of the Songling Xuemaikang capsule therapy used for hypertension. The present study aimed to investigate the effects and underlying mechanisms of MWS‑19 on hydrogen peroxide (H2O2)‑induced apoptosis in human umbilical vein endothelial cells (HUVECs).

Two new sesquiterpene glycosides isolated from the fresh needles of Pinus massoniana Lamb.

Two new sesquiterpene glycosides, namely massonside A (1) and massonside B (2), were isolated from the n-Bu extract of the fresh needles of Pinus massoniana Lamb. Their structures were established by 1D, 2D nuclear magnetic resonance and high-resolution mass spectrometry. Their biological activities were profiled by the anti-HBV and anti-HCV assays.

The Effects of Puerarin on Rat Ventricular Myocytes and the Potential Mechanism.

Puerarin, a known isoflavone, is commonly found as a Chinese herb medicine. It is widely used in China to treat cardiac diseases such as angina, cardiac infarction and arrhythmia. However, its cardioprotective mechanism remains unclear.

[Study on flavonoid chemical constituents contained in Memorialis hirta].

Objective: To study the chemical constituents of Memorialis hirta.

Method: Compounds were isolated and purified by multiple methods, and their structures were identified based on physicochemical property and spectrum data.

Result: 12 compounds were isolated from ethyl acetate from 95% ethanol extracts of M.

[Flavonoid glycosides from Androsace umbellata].

Objective: To study the chemical constituents of Androsace umbellata.

Method: Many chromatography means were used in separation and purification, and the structures of all compounds were identified by the means of spectroscopic analysis and physico-chemical properties.

Result: 10 compounds were elucidated as kaempferol 3-O-(3-O-acetyl-)-alpha-L-rhamnopyranoside(1), kaempferol 3-O-(2-O-acetyl-)-alpha-L-rhamnopyranoside(2), kaempferol 7-O-alpha-L-rhamnopyranoside(3), kaempferol 3-O-alpha-L- rhamnopyranoside(4), kaempferol 3-O-beta-D-glucopyranoside(5), kaempferol 3-O-(3-O-acetyl-)-a-L-rhamnopyranosyl-7-O-alpha-L- rhamnopyranoside(6), kaempferml 3-O-(4-O-acetyl-)-alpha-L-rhamnopyranosyl-7-O-alpha-L-rhamnopyranoside(7), quercetin 3-O-alpha-L- rhamnopyranoside(8), quercetin 3-O-beta-D-glucopyranoside(9) and myricetin 3-O-beta-D-glucopyranoside (10), respectively.