Modulation optimization method for seven-level SHEPWM inverter based on EPSO algorithm.

Selective Harmonic Elimination Pulse Width Modulation (SHEPWM) has excellent harmonic characteristics, but its nonlinear transcendental system of equations is difficult to be solved, and the practical application encounters a bottleneck. In this paper, a modulation optimization method for seven-level SHEPWM inverter based on the Evolutionary Particle Swarm Optimization (EPSO) algorithm is proposed to address this problem, so that the algorithm quickly converges to the global optimum solution. The EPSO algorithm incorporates a population optimization strategy in two phases to improve the population diversity in real time.

Male sterility is related to the imbalance of reactive oxygen species homeostasis in Prunus sibirica.

Prunus sibirica is an economically important forest tree with great development prospects. To study the mechanisms of male sterile P. sibirica, we compared the phenotypic, cytological, and physiological characteristics of male sterile clone 1 with those of male fertile clone 60.

Metagenome-based characterization of the gut bacteriome, mycobiome, and virome in patients with chronic hepatitis B-related liver fibrosis.

Introduction: The gut microbiota is believed to be directly involved in the etiology and development of chronic liver diseases. However, the holistic characterization of the gut bacteriome, mycobiome, and virome in patients with chronic hepatitis B-related liver fibrosis (CHB-LF) remains unclear.

Methods: In this study, we analyzed the multi-kingdom gut microbiome (i.

Effects of Zhenggan Huayu decoction combined with entecavir on gut microbiota in patients with chronic hepatitis B fibrosis.

Objective: To evaluate the effects of Zhenggan Huayu decoction (, ZGHY) combined with entecavir (ETV) on the gut microbiota in patients with chronic hepatitis B (CHB) fibrosis.

Methods: A total of 59 CHB-related fibrosis patients were enrolled and treated with ZGHY combined with ETV (ZGHY + ETV) and ETV alone. Fecal samples were collected from patients at weeks 0, 12, and 24 after treatment and gut microbiota were analyzed by 16S rRNA gene sequencing.

[Retracted] MicroRNA‑326 inhibits cell proliferation and invasion, activating apoptosis in hepatocellular carcinoma by directly targeting LIM and SH3 protein 1.

Following the publication of the above paper, it was drawn to the Editors' attention by a concerned reader that various panels showing data from flow cytometric experiments in Figs. 2E, 5E and 6E, and the cell migration and invasion assay data shown in Fig. 2D and 6D, were strikingly similar to data appearing in different form in other articles by different authors.

Application of artificial intelligence system for screening multiple fundus diseases in Chinese primary healthcare settings: a real-world, multicentre and cross-sectional study of 4795 cases.

Background/aims: This study evaluates the performance of the Airdoc retinal artificial intelligence system (ARAS) for detecting multiple fundus diseases in real-world scenarios in primary healthcare settings and investigates the fundus disease spectrum based on ARAS.

Methods: This real-world, multicentre, cross-sectional study was conducted in Shanghai and Xinjiang, China. Six primary healthcare settings were included in this study.

An Ultrasonic Reverse Time Migration Imaging Method Based on Higher-Order Singular Value Decomposition.

An ultrasonic reverse time migration imaging method, based on high-order singular value decomposition, is proposed in the study to solve the problems of low signal-to-noise ratio (SNR) and excessive artifacts in defect ultrasonic detection imaging results of materials with high noise levels. In this method, based on the 3D structural properties of the ultrasonic full-matrix capture data, higher-order singular value decomposition is directly performed with the 3D data. The method overcomes the difficulty in selecting the number of singular values in the original singular value decomposition noise-reduction algorithm and realizes the one-step noise reduction processing of all the signals.

Production of Functional Hepatobiliary Organoids from Human Pluripotent Stem Cells.

The research on human hepatobiliary development and disorders has been constrained by minimal access to human fetal tissue, and low accuracy of animal models. To overcome this problem, we have established a system for the differentiation of human pluripotent stem cells (hPSCs) into functional hepatobiliary organoids (HBOs). We have previously reported that our 45-d approach closely mimics key stages of hepatobiliary development, starting with the differentiation of hiPSC into endoderm and a small part of mesoderm, and subsequently into hepatoblast-like cells, followed by the parallel generation of hepatocyte-like cells and cholangiocyte-like cells, formation of immature HBO expressing early hepatic and biliary markers, and mature HBO displaying hepatobiliary functionality.

Fault diagnosis of rolling bearings with recurrent neural network-based autoencoders.

As the rolling bearings being the key part of rotary machine, its healthy condition is quite important for safety production. Fault diagnosis of rolling bearing has been research focus for the sake of improving the economic efficiency and guaranteeing the operation security. However, the collected signals are mixed with ambient noise during the operation of rotary machine, which brings great challenge to the exact diagnosis results.

MicroRNA-326 inhibits cell proliferation and invasion, activating apoptosis in hepatocellular carcinoma by directly targeting LIM and SH3 protein 1.

Hepatocellular carcinoma (HCC) is the fifth-most common cancer and third leading cause of cancer-related deaths worldwide. Increasing evidence indicates that dysregulation of microRNAs is often observed in HCC, and has been extensively investigated in terms of cancer formation, progression, diagnosis, therapy, and prognosis. Recently, microRNA-326 (miR-326) has been demonstrated to play important roles in multiple types of human cancer.

A distributed model predictive control based load frequency control scheme for multi-area interconnected power system using discrete-time Laguerre functions.

This paper proposes a distributed model predictive control based load frequency control (MPC-LFC) scheme to improve control performances in the frequency regulation of power system. In order to reduce the computational burden in the rolling optimization with a sufficiently large prediction horizon, the orthonormal Laguerre functions are utilized to approximate the predicted control trajectory. The closed-loop stability of the proposed MPC scheme is achieved by adding a terminal equality constraint to the online quadratic optimization and taking the cost function as the Lyapunov function.

A novel AKT inhibitor, AZD5363, inhibits phosphorylation of AKT downstream molecules, and activates phosphorylation of mTOR and SMG-1 dependent on the liver cancer cell type.

Due to frequent phosphoinositide 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway dysregulation, AKT is typically accepted as a promising anticancer therapeutic target. mTOR, in particular, represents a suitable therapeutic target for hepatocellular carcinoma, whilst suppressor with morphogenetic effect on genitalia family member-1 (SMG-1) is believed to serve a potential tumor suppressor role in human cancer. Despite SMG-1 and mTOR belonging to the same PI3K-related kinase family, the interactions between them are not yet fully understood.

Development and characterization of 25 EST-SSR markers in Pinus sylvestris var. mongolica (Pinaceae).

Premise Of The Study: A set of novel expressed sequence tag (EST) microsatellite markers was developed in Pinus sylvestris var. mongolica to promote further genetic studies in this species. •

Methods And Results: One hundred seventy-five EST-simple sequence repeat (SSR) primers were designed and synthesized for 31,653 isotigs based on P.

Isolation and expression profiles of gibberellin metabolism genes in developing male and female cones of Pinus tabuliformis.

Gibberellins (GAs) are important in the floral regulatory networks of angiosperm plants. Several lines of evidence suggest that GAs also play a pivotal role in conifer male and female cone development. To gain new insights into the GA metabolism pathway in conifer trees and the role of GA metabolism in male and female cone development, we identified GA metabolism genes in Pinus tabuliformis.

1-Benzyl-idene-4-ethyl-thio-semicarbazide.

The title compound, C(10)H(13)N(3)S, was prepared by the reaction of 4-ethyl-thio-semicarbazide and benzaldehyde. The dihedral angle between the benzene ring and the thio-urea unit is 8.96 (7)° and an intra-molecular N-H⋯N hydrogen bond generates an S(5) ring.