Publications by authors named "Yuna So"

Article Synopsis
  • A 40-year-old Japanese man with HIV experienced a decline in consciousness after two years of not receiving treatment, showing severe weight loss and a critically low CD4+ lymphocyte count.
  • He was diagnosed with disseminated Mycobacterium avium infection and pneumocystis pneumonia, and a brain biopsy confirmed varicella zoster virus (VZV) encephalitis.
  • The patient was treated with antiretroviral therapy and intravenous acyclovir, leading to survival but with ongoing neurological complications; VZV encephalitis is rare and carries a poor prognosis in AIDS patients.
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A 44-year-old HIV-positive man diagnosed with diffuse large B-cell lymphoma in 2021 achieved complete remission with six cycles of R-CHOP therapy but had a relapse in November 2022. ESHAP therapy failed to induce remission, leading to complete remission with four cycles of Pola-BR therapy. Post-failure of autologous stem cell harvest, cord blood transplantation (CBT) was performed in June 2023.

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Objectives: To address the paucity of HIV-related lymphoma (HRL)-specific prognostic scores for the Japanese population by analyzing domestic cases of HRL and constructing a predictive model.

Design: A single-center retrospective study coupled with a review of case reports of HRL.

Methods: We reviewed all patients with HRL treated at our hospital between 2007 and 2023 and conducted a comprehensive search for case reports of HRL from Japan using public databases.

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