Publications by authors named "Yun-yi Xu"
Article Synopsis
- Hypoxic-ischaemic encephalopathy (HIE) is a serious condition in newborns leading to disabilities and death, and while hypothermia therapy helps, more effective treatments are needed.
- Researchers investigated the effects of human placenta-derived mesenchymal stem cells (PD-MSCs) on HIE in rats, comparing them with a saline solution and observing outcomes over time.
- Results indicated that PD-MSC transplantation improved motor skills and memory in HIE rats, with the best outcomes seen when treatment was given early (at day 7), and demonstrated positive changes in brain health and significantly altered protein levels related to cell survival and inflammation.
Objective: To improve evidence-based care in the management of tuberculosis, we retrospectively analyzed the bacterial types and drug sensitivity test results of mycobacteria in Guangzhou over the past twelve years (from July 1998 to March 2010).
Methods: Over these twelve years, a total of 14 095 mycobacterial strains isolated from different samples were subjected to type identification and drug sensitivity tests according to the Standard Protocols of Laboratory Diagnostics for Tuberculosis by the Chinese Antituberculosis Association. Chi-square test was performed for statistical analyses for comparisons between groups.
The aim of this study was to characterize 160 clinical Mycobacterium tuberculosis isolates from Guangdong with respect to their drug susceptibility phenotypes to three common anti-tuberculosis drugs, isoniazid (INH), rifampin (RIF) and streptomycin (SM), and with respect to genetic mutations in the most commonly corresponding resistance genes (katG, rpoB and rpsL). The drug susceptibility profiles were evaluated by the absolute concentration method, and genetic mutations in the corresponding resistance genes were identified by DNA sequencing. Among these isolates, 33.
View Article and Find Full Text PDFMycobacterium tuberculosis and Mycobacterium bovis are pathogenic bacterial species in the genus Mycobacterium and the causative agents of most cases of tuberculosis (TB). Detection of M. tuberculosis and M.
View Article and Find Full Text PDF[Effects of glucocorticoids on tuberculous pleural effusion: experiment with rats].
Zhonghua Yi Xue Za Zhi
August 2008
Objective: To explore the effects of systemic glucocorticoid treatment on tuberculous pleural effusion.
Methods: Ninety Wistar rats were intrapleurally injected with 0.03 mg of standard human Mycobacterium tuberculosis to establish models of tuberculous pleural effusions and then were randomly divided into 2 equal groups both without anti-tuberculosis treatment: glucocorticoids group (GG) undergoing intramuscular injection of 0.