Publications by authors named "Yun-xiang Zeng"
[Diagnostic values of the clinical characteristics of chronic cough].
Zhonghua Jie He He Hu Xi Za Zhi
June 2009
Objective: To evaluate whether the clinical characteristics of chronic cough were helpful in determining its specific causes.
Methods: Patients with chronic cough were evaluated by a validated systematic diagnostic protocol. The patients with identified single cause were divided into 4 groups accordingly: cough-variant asthma (CVA), upper airway cough syndrome (UACS) or post-nasal drip syndrome (PNDS), eosinophilic bronchitis (EB), gastroesophageal reflux related cough (GERC), and the characteristics of the timing, character, onset and associated manifestations of chronic cough in different causes were compared.
[Characteristics of airway inflammatory cells and mediators in eosinophilic bronchitis patients].
Zhonghua Jie He He Hu Xi Za Zhi
September 2005
Article Synopsis
- - The study analyzed airway inflammation in patients with eosinophilic bronchitis (EB) by examining sputum and bronchoalveolar lavage fluid (BALF) from various groups, including patients with cough variant asthma (CVA), bronchial asthma, and healthy controls.
- - Results indicated that patients with EB had a significant percentage of eosinophils in their sputum compared to healthy controls, and differences in inflammatory mediators like eosinophilic cationic protein (ECP) and leukotriene C(4) were also observed across the groups.
- - The findings suggest that eosinophilic infiltration is primarily localized to the central airways in EB, highlighting distinct inflammatory features compared to CVA and asthma patients
[The role of airway neurogenic inflammation in gastro-esophageal reflux induced cough].
Zhonghua Jie He He Hu Xi Za Zhi
August 2005
Objective: To investigate the role of airway neurogenic inflammation in the pathogenesis of gastro-esophageal reflux induced cough (GERC).
Methods: Sputum was induced by hypertonic saline aerosol inhalation in 20 patients with GERC (GERC group), 10 healthy subjects (normal control group) and 8 patients with chronic cough due to other causes but complicated with gastro-esophageal reflux diseases (GERD, GERD group). Airway mucosal biopsy was performed in 6 patients with GERC and 4 patients with GERD using flexible fiberoptic bronchoscopy.