Inhibition of miR-22 enhanced the efficacy of icotinib plus pemetrexed in a rat model of non-small cell lung cancer.

Objectives: To investigate the role of miR-22 in the efficacy of combined icotinib (BPI-2009H) and pemetrexed (LY-231514) on tumor growth and apoptosis in rats with non-small cell lung cancer (NSCLC).

Materials And Methods: Rats were injected with HCC827 cells, which were transfected with anti-miR-22, followed by the treatment of BPI-2009H and/or LY-231514. MTT assay was used to detect the inhibition rate of HCC827 cells.

Diagnosis and comprehensive treatment of esophageal leiomyoma: clinical analysis of 77 patients.

To investigate the diagnosis and comprehensive treatment of esophageal leiomyoma. The clinical data of 77 cases of esophageal leiomyoma patients were analyzed between 2005 and 2013. Its diagnosis, treatment and prognosis were analyzed.

Diagnosis and multi-modality treatment of adult pulmonary plastoma: Analysis of 18 cases and review of literature.

The clinical data of 18 patients with PB from April 1989 to April 2013 was analyzed retrospectively, including 11 men and 7 women, aged 45 and 76 years old (mean 53 years). There were 12 cases of PB occurring in right lung and other cases in left lung. Among them, 3 patients had no symptoms, and 15 patients displayed symptoms of cough, chest pain, asthenia or minor haemoptysis.

Treatment of 336 cases of chest trauma.

Objective: To summarize the clinical features, diagnosis and treatment of chest trauma.

Methods: A retrospective analysis was conducted among 336 cases of chest trauma admitted to our hospital from January 2009 to May 2011.

Results: Out of all cases, 325 were cured, accounting for 96.

Surgical treatment and prognosis of octogenarians with non-small cell lung cancer.

Objective: To explore the clinical characteristics, surgical treatment and prognosis of non-small cell lung cancer (NSCLC) among elderly patients over 80 years.

Methods: The clinical data, surgical methods, perioperative management, postoperative complications and prognosis of 52 NSCLC patients aged over 80 years were retrospectively analyzed.

Results: Out of 52 cases, 27 had a long-term smoking history (51.

[Comparative study on molecular staging of lymph nodes in non-small cell lung cancer patients].

Background And Objective: The postoperative survival of patients with non-small cell lung cancer (NSCLC) is mainly determined by clinical pathologic stage. However, recurrence is not rare in stage I NSCLC patients. This study was to explore whether conventional pathologic stages of some NSCLC were underestimated.

[Comparative study for detecting micrometastases of lymph nodes in patients with lung cancer].

Objective: To set up a new method to detect occult micrometastases of lymph nodes in patients with no-small-cell lung cancer (NSCLC).

Methods: We had detected 195 lymph node samples taken from 25 patients with NSCLC during the operations. Each lymph node sample was divided into two same parts in size.

[Clinicopathological study on nodal molecular staging of non-small-cell lung cancer].

Objective: To investigate the practicability of detecting the micrometastasis in lymph nodes of no-small-cell lung cancer (NSCLC) by means of reverse transcriptase-polymerase chain reaction (RT-PCR).

Methods: Regional lymph node samples were collected during operation from 25 patients with NSCLC randomly selected. The lymph node sample from each patient was divided into 2 groups: lymph nodes of hilum of lung and of mediastinum.

[Clinical pathological study on nodal micrometastases of non-small-cell lung cancer].

Objective: To investigate the practicability of detecting the micrometastases in lymph nodes of no-small-cell lung cancer (NSCLC) by means of the immunohistochemical (IHC) staining.

Methods: The lymph node samples were taken from the patients with NSCLC during the operations. Firstly, each resulting tissue block was processed for routine paraffin embedding.

[Long-term outcome of bronchoplastic procedures in the treatment of lung cancer].

Objective: To assess the value of bronchoplastic procedures in surgical treatment for bronchogenic carcinoma.

Methods: Bronchoplastic procedures were performed in 78 patients with bronchogenic carcinoma from August 1976 to December 2002. There were 67 patients with squamous cell carcinoma (86%).