Publications by authors named "Yun-Zi Zhao"
Background: Tpeak-Tend interval (TpTe), a measurement of transmural dispersion of repolarization (TDR), has been shown to predict ventricular tachyarrhythmia in cardiac resynchronization therapy with defibrillator (CRT-D) patients. However, the ability of TpTe to predict ventricular tachyarrhythmia and mortality for heart failure patients with a cardioverter-defibrillator (ICD) is not clear. The purpose of this study was to assess the predictive ability of TpTe in heart failure patients with ICD.
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- The study examines the effects of cardiac resynchronization therapy (CRT) on the Tpeak-Tend (TpTe) interval, which is linked to heart failure mortality, aiming to clarify its impact on repolarization dispersion and ventricular arrhythmia risk.
- A total of 101 patients receiving CRT-defibrillator treatment were evaluated, showing an initial increase in TpTe followed by a decrease at one-year follow-up, with significant differences in left ventricular remodeling and arrhythmia rates based on whether TpTe was shortened.
- The findings suggest that while acute TpTe changes post-CRT have limited impact on long-term heart remodeling and ventricular arrhythmia, meaningful long-term improvements occur for patients with a shortened TpTe at one year.