Postoperative cognitive dysfunction (POCD) is a prevalent neurocognitive complication of anesthesia and surgery. Metformin, a widely used antidiabetic drug, has neuroprotective properties and improves cognitive impairment and memory deficits. However, the mechanisms underlying its action in improving cognitive dysfunction after anesthesia and surgery remain unclear.
View Article and Find Full Text PDFSkin epidermis secretes apical extracellular matrix (aECM) as a protective barrier from the external environment. The aECM is highly dynamic and constantly undergoes remodeling during animal development. How aECM dynamics is temporally regulated during development, and whether and how its mis-regulation may impact epidermal cell morphology or function remains to be fully elucidated.
View Article and Find Full Text PDFMitochondrial DNA B Resour
October 2021
is an important medicinal herb widely used in East Asia. In this study, we report the first complete chloroplast genome sequence of using next-generation sequencing technology. The chloroplast genome size of was 156,981 bp.
View Article and Find Full Text PDFProgrammed cell death (PCD) is a common cell fate in metazoan development. PCD effectors are extensively studied, but how they are temporally regulated is less understood. Here, we report a mechanism controlling tail-spike cell death onset during Caenorhabditis elegans development.
View Article and Find Full Text PDFMitochondrial DNA B Resour
July 2021
The first complete chloroplast genome of Turcz. var (Miq.) Ling.
View Article and Find Full Text PDFMitochondrial DNA B Resour
July 2021
As an important medicinal herb, no complete organelle molecular data has been reported for . In this study, the first complete chloroplast genome of Makino was sequenced and assembled. The genome is 155,802 bp in length and contained 124 encoded genes in total, including 75 protein-coding genes, 10 ribosomal RNA genes, and 39 transfer RNA genes.
View Article and Find Full Text PDFSpatiotemporal regulation of cell migration is crucial for animal development and organogenesis. Compared to spatial signals, little is known about temporal signals and the mechanisms integrating the two. In the Caenorhabditis elegans hermaphrodite, the stereotyped migration pattern of two somatic distal tip cells (DTCs) is responsible for shaping the gonad.
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