Publications by authors named "Yun-Xin Zhang"

This study aims to understand the repercussions of the COVID-19 pandemic on hospitalized patients with peripheral arterial disease (PAD) in China, who did not contract SARS-CoV-2. We conducted a multicenter cross-sectional analysis comparing the characteristics and outcomes of hospitalized PAD patients across two distinct periods: Pre-pandemic (P1, from January 2018 to December 2019) and during the pandemic (P2, from January 2020 to December 2021). During P1, 762 hospitalized patients were treated, with an average age of 72.

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Article Synopsis
  • The inferior vena cava filter helps prevent fatal pulmonary embolism but can cause thrombosis as a complication, which can be treated with AngioJet rheolytic thrombectomy (ART) or catheter-directed thrombolysis (CDT).
  • A study analyzed 65 patients with filter-related caval thrombosis to compare the effectiveness of ART and CDT in terms of thrombus clearance, complications, and other clinical outcomes.
  • Results indicated that both treatments had a 100% technical success rate, with both groups showing significant reduction in limb circumference, but ART required significantly less urokinase than CDT, and there were more minor bleeding incidents in the CDT group.
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Objective: To compare the intraoperative safety profiles of transurethral plasmakinetic resection of the prostate (PK-TURP) with transurethral plasmakinetic endoscopic enucleation of the prostate (PK-EEP) in the treatment of benign prostatic hyperplasia (BPH) based on endoscopic surgical monitoring system (ESMS).

Methods: A total of 128 patients who were diagnosed with BPH were stratified based on prostate volume (PV) and accepted PK-EEP or PK-TURP treatment at 1:1 ratio. The ESMS as a novel method was used to monitor blood loss and fluid absorption during the operation.

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Purpose: To explore the significance of traditional vascular reconstruction and covered stent for limb salvage after subclavian artery injury.

Methods: Patients with subclavian artery injury admitted to Beijing Jishuitan Hospital from January 2010 to December 2018 were retrospectively analyzed. All the injuries have been confirmed by intraoperative exploration, computed tomography angiography or digital subtraction angiography.

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Article Synopsis
  • Traumatic peripheral vascular injuries are major causes of disability and death, commonly resulting from penetrating or blunt trauma, and sometimes due to medical procedures (iatrogenic injuries).
  • Various types of vascular injuries can occur, leading to severe clinical manifestations like shock and limb necrosis, with advanced imaging techniques playing a key role in diagnosis.
  • Effective treatment focuses on immediate hemorrhage control and restoring blood flow, using surgical methods like suturing or grafting, along with promising endovascular techniques; however, more research is needed for optimal management.
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  • The study analyzes the treatment of traumatic innominate arterial injuries at Beijing Jishuitan Hospital from January 2016 to July 2018, utilizing retrospective patient data for analysis.
  • Seven patients were included, primarily young males (average age 29.43 years), and injuries were caused by various incidents like road accidents and stabbings, with all presenting hemorrhagic shock upon admission.
  • Treatment approaches varied, with most injuries treated with stents or vascular grafts, and there were no perioperative deaths, though one patient experienced cerebral infarction due to anticoagulation issues during recovery.
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Our previous study has reported that ginsenoside-Rd significantly inhibited the production of pro-inflammatory cytokines and mediators in carrageenan (Carr)-induced rat paw edema, which might be due to its blocking of the nuclear factor-κB (NF-κB) signaling pathway. The aim of the present study was to clarify the more detailed mechanisms of anti-inflammatory activity of ginsenoside-Rd in Carr-induced rat paw edema model. Rats were pretreated with dexamethasone or ginsenoside-Rd 1 h before the Carr injection.

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Purpose: To study the clinical effect of osteotome sinus floor elevation (OSFE) combined with simultaneous implant placement in the treatment of edentulous posterior maxilla subject to insufficient bone height in the periodontally compromised patients.

Methods: Forty-seven Straumanns implants were placed in the posterior maxilla in 35 patients with the procedure of OSFE. The final prostheses were restored after 3 to 6 months.

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Background And Aims: Despite previous reports implying a role of β2-microglobulin (β2M) in the development of prostate cancer (PCa), the correlation of serum β2M with the clinicopathological features, therapy efficacy and prognosis of patients with PCa have not been fully clarified. The present study aims to investigate the serum levels of β2M in patients with PCa and explore the potential use of β2M as a tumor marker for diagnosis, treatment and prognosis of PCa.

Methods: Serum β2M levels in 120 patients with PCa, 50 patients with benign prostate hyperplasia (BPH) and 85 healthy age-matched controls were measured by enzyme immunoassay.

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Background: Experimental data suggest that mitochondria is involved in tumorigenesis. However, little is known about the qualitative and quantitative changes of mtDNA in colorectal cancer tissues. We therefore conducted possible correlations of the mitochondrial DNA (mtDNA) copy number in colorectal cancer (CRC) with clinical and pathological findings and CRC prognosis.

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Objectives: This clinical trial aimed (1) to evaluate the predictability of the osteotome sinus floor elevation (OSFE) technique, (2) to study the influence of simultaneous grafting on the clinical success of placing dental implants in the posterior maxilla using OSFE and (3) to observe the bone changes in the elevated space with OSFE without grafting.

Material And Methods: Two hundred and eighty Straumann implants were placed in the posterior maxillae of 202 patients using OSFE. One hundred and ninety-one implants were placed in 125 patients without grafting.

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Objective: To study the relationship between the abnormality of mitochondrial DNA (mtDNA) copy number and the clinical parameters and microsatellite instability (MSI) in colorectal cancer.

Methods: Total DNA was extracted from cancer and pericancer tissue from 50 colorectal cancer (CRC) biopsy samples. Non-coding region sequencing was done and the copy number of mtDNA was quantitated with real-time PCR in mitochondrial ND1 gene.

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Purpose: To study the clinical effect of osteotome sinus floor elevation (OSFE) without bone grafting combined with simultaneous implant placement in the treatment of edentulous posterior maxilla subject to insufficient bone height.

Methods: Sixty-seven Straumann SLA implants were placed in the posterior maxilla in 50 patients. The residual bone height (RBH) was (5.

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Objective: To investigate the changes in bacterial proliferation and the time of infection occurrence in dogs wounded by gunshot in seawater.

Method: Fourteen canine models of gunshot wound in seawater were established, with another 2 dogs receiving the wound without seawater immersion serving as control. Gross observation and quantitative bacterial analysis were performed at 0, 6, 12 and 24 h after the injury respectively, and two dynamic models for the bacterial growth were set up on the basis of statistical analysis of the results.

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