Publications by authors named "Yun-Xiang Lv"
Article Synopsis
- Exposure to particulate matter (PM) worsens allergic airway diseases by increasing inflammation and symptoms, but the exact molecular mechanisms are not well understood.* -
- The study used mouse models to show that PM exposure leads to inflammatory responses involving TLR2 and the NLRP3 inflammasome, particularly in allergic mice, resulting in elevated inflammatory cytokines.* -
- Inhibiting the TLR2/NF-κB/NLRP3 signaling pathway may serve as a potential therapeutic approach to reduce allergic airway inflammation triggered by PM exposure.*
Background: Plasma levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) are elevated in subjects with COPD, and high plasma NT-proBNP levels are correlated with a poor prognosis. Thus, it is crucial to decrease the plasma NT-proBNP levels at the early stage of disease. We aimed to assess the effects of short-term treatment of irbesartan and hydrochlorothiazide on plasma NT-proBNP levels and health-related quality of life (HRQOL) in subjects with acute exacerbations of COPD (AECOPD).
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