A novel pyrazole-pyrazoline fluorescent probe for the detection of Cu and Fe in living cells.

Copper ions and iron ions are abundant metal ions in nature, and are also essential trace elements in the human body, playing a crucial role in various physiological activities. However, the detection of copper and iron ions also poses significant challenges. This article reports the synthesis of a novel fluorescent probe X based on the pyrazole structure, which exhibits unique optoelectronic properties, strong biological activity, good selectivity, excellent detection limit, high sensitivity, and its structure was characterized by H NMR, C NMR, and HR-ESI-MS.

Synthesis and Application of Specific NH Fluorescent Probes with AIE Effect Based on Pyrazole Structure.

Two fluorescent probes, Y were synthesized from 2-acetonaphthone, 4-acetylbiphenyl, and phenyl hydrazine by Vilsmeier-Haack reaction and Knoevenagel condensation. Their recognition efficacies for NH were tested by UV-visible absorption spectroscopy and fluorescence emission spectroscopy. The recognition mechanism were studies by density-functional theory calculations, and the effect of pH on NH recognition was also studied.

Bis-chalcone Fluorescent Probe for Hydrazine Ratio Sensing in Environment and Organism.

In this paper, four novel hydrazine fluorescent probes X-X with bis-chalcone structure were designed and synthesized. Through the measurement of its optical properties, it is found that it can quickly identify hydrazine, high sensitivity, low detection limit, and good anti-interference ability. The recognition of hydrazine by probes X-X is not affected in the pH range of 4-10, X has the highest sensitivity, and the detection limit is as low as 0.

Cinnamyl Chalcone Based AIE Fluorescent Probes for Sensitive Detection of Hydrazine and its Application in Living Cells.

Widely utilized in the chemical industry and agriculture, hydrazine is easily absorbed by living things and can cause physical harm when in touch for an extended period of time. As a result, a novel cinnamaldehyde chalcone C5 was produced by Friedel Crafts process and aldol condensation reaction. Triphenylamine was used as the raw material for hydrazine determination in both reactions.

Novel Bis-pyrazoline Fluorescent Probe for Cu and Fe Detection and Application in Cell Imaging.

A fluorescent probe Y((1,1'-([1,1'-biphenyl]-4,4'-diylbis(3-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazole-5,1-diyl)) bis(ethan-1-one))) was designed and synthesized, which could be used to Cu and Fe sensors. Through the study of optical properties, the probe Y shows good selectivity and sensitivity to Cu and Fe in aqueous tetrahydrofuran solution [10.0 mM HEPES, pH 7.

Aggregation-induced Emission Properties of Triphenylamine Chalcone Compounds.

Two triphenylamine chalcone derivatives 1 and 2 were synthesized through the Vilsmeier-Haack reaction and Claisen-Schmidt condensation reaction. Through ultraviolet absorption spectroscopy and fluorescence emission spectroscopy experiments, it was confirmed that these two compounds exhibited good aggregation-induced emission (AIE) behavior in ethanol/water mixtures. The solvent effect test showed with the increase of the orientation polarizability of the solvent, the Stokes shift in the solvent of compound 1 and compound 2 shows a linear change trend.

A Novel Fluorescent Probe Based on Pyrazole-Pyrazoline for Fe (III) Ions Recognition.

Firstly, a novel pyrazole-pyrazoline fluorescent probe was developed and synthesized. The probe can be used to determine Fe ions in a series of cations in tetrahydrofuran aqueous solution with high selectivity and high sensitivity. After the addition of iron ions, the fluorescence intensity is significantly reduced, Its structure was characterized by H NMR, C NMR and HR-ESI-MS.

A novel coumarin-derived acylhydrazone Schiff base gelator for synthesis of organogels and identification of Fe.

A novel coumarin-derived acylhydrazone Schiff base fluorescent organogel (G) was designed and synthesized. Gelator G can form stable organogels in isopropanol, tert-amyl alcohol, n-butanol and phenylamine. The organogel could be converted to solution by heating and the solution could be restored to gel state by cooling.

Synthesis of nitrogen-doped graphene quantum dots (N-GQDs) from marigold for detection of Fe ion and bioimaging.

Graphene quantum dots (GQDs) are synthesized by the method of high-temperature pyrolysis from marigold granules and subsequently nitrogen-doped graphene quantum dots (N-GQDs) are synthesized from ethylenediamine by hydrothermal treatment, which shows a strong blue emission with 7.84% quantum yield (QY). This will be used in detection of Fe in water environments and the field of bioimaging.

A novel biphenyl-derived salicylhydrazone Schiff base fluorescent probes for identification of Cu and application in living cells.

A novel biphenyl-derived salicylhydrazone Schiff base (BSS) fluorescent probes for highly sensitive and selective identification of Cu has been synthesized. In addition, the recognition has been proved experimentally. The results indicated that the complex forms a 1:1 complex with Cu shows fluorescent quenching.

A new pyrazoline-based probe of quenched fluorescent reversible recognition for Cu and its application in cells.

A new pyrazoline-based probe D was designed and synthesized, which can be used as a highly sensitive, selective and reversible recognizing fluorescent to detect Cu. The recognition properties of this compound was investigated by UV-vis absorption and fluorescence spectrophotometry. The results showed that the probe D forms a 1:1 complex with Cu and displayed a linear fluorescence response to Cu with a detection limit of 1.