Evaluation of the learning curve of laser peripheral iridectomy: the 20 case reaches the turning point.

Aim: To explore the learning curve for ophthalmologists at the start of laser peripheral iridectomy (LPI) training.

Methods: The learning curve of 4 doctor groups without previous LPI experience was studied. Three main parameters of LPI were reviewed: total energy, argon energy and neodymium-doped yttrium aluminum garnet (Nd:YAG) energy.

Eye Habits Affect the Prevalence of Asthenopia in Patients with Myopia.

Purpose: This study aims to explore the risk factors of asthenopia in the myopic population.

Methods: In this cross-sectional study, myopia patients were inquired about their eye habits and were requested to complete an asthenopia questionnaire and ocular examinations. Age, gender, occupation, anisometropia, eye care education, weekly outdoor activity time, duration of continuous near work, daily screen time, dry eye, near phoria, and binocular accommodative facility were calculated using the Student's test-test, Mann Whitney test, and Pearson's chi-square test.

The Clinical Features of Graves' Orbitopathy with Elevated Intraocular Pressure.

Background: To investigate the clinical characteristics of Graves' orbitopathy (GO) with elevated intraocular pressure (IOP) using the European Group of Graves' Orbitopathy (EUGOGO) system.

Methods: In this retrospective study, the clinical data of GO patients with elevated IOP (≥21 mmHg) were collected in Sun Yat-sen Memorial Hospital from January 2010 to June 2016. The demographic characteristics, clinical history of thyroid disease and GO, and ocular examination data were evaluated, and the activity and severity of GO were classified.

TLR7 deficiency contributes to attenuated diabetic retinopathy via inhibition of inflammatory response.

Diabetic retinopathy (DR) is a major microvascular complication of diabetes, resulting in neuronal dysfunction, retinal vascular leakage, and apoptosis within the retina. Innate immunity plays an important role in the pathogenesis of type 2 diabetes (T2D) and related complications. The toll-like receptors (TLRs), central to innate immunity, are essential participants in the progression and pathogenesis of the disease and its complications.